Hmdb loader
Identification
HMDB Protein ID HMDBP08425
Secondary Accession Numbers
  • 14137
Name GTPase IMAP family member 4
Synonyms
  1. IAN-1
  2. Immunity-associated nucleotide 1 protein
  3. Immunity-associated protein 4
  4. hIAN1
Gene Name GIMAP4
Protein Type Unknown
Biological Properties
General Function Involved in GTP binding
Specific Function Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium
Pathways Not Available
Reactions Not Available
GO Classification
Function
purine nucleotide binding
binding
nucleotide binding
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:7
Locus 7q36.1
SNPs GIMAP4
Gene Sequence
>990 bp
ATGGCAGCCCAATACGGCAGTATGAGCTTCAACCCCAGCACACCAGGGGCCAGTTATGGG
CCTGGAAGGCAAGAGCCCAGAAATTCCCAATTGAGAATTGTGTTAGTGGGTAAAACCGGA
GCAGGAAAAAGTGCAACAGGAAACAGCATCCTTGGCCGGAAAGTGTTTCATTCTGGCACT
GCAGCAAAATCCATTACCAAGAAGTGTGAGAAACGCAGCAGCTCATGGAAGGAAACAGAA
CTTGTCGTAGTTGACACACCAGGCATTTTCGACACAGAGGTGCCCAATGCTGAAACGTCC
AAGGAGATTATTCGCTGCATTCTTCTGACCTCCCCAGGGCCTCATGCTCTGCTTCTGGTG
GTTCCACTGGGCCGTTACACTGAGGAAGAGCACAAAGCCACAGAGAAGATCCTGAAAATG
TTTGGAGAGAGGGCTAGAAGTTTCATGATTCTCATATTCACCCGGAAAGATGACTTAGGT
GACACCAATTTGCATGACTACTTAAGGGAAGCTCCAGAAGACATTCAAGACTTGATGGAC
ATTTTCGGTGACCGCTACTGTGCGTTAAACAACAAGGCAACAGGCGCTGAGCAGGAGGCC
CAGAGGGCACAGTTGCTGGGCCTGATCCAGCGCGTGGTGAGGGAGAACAAGGAAGGCTGC
TACACTAATAGGATGTACCAAAGGGCGGAGGAGGAGATCCAGAAGCAAACACAAGCAATG
CAAGAACTCCACAGAGTGGAGCTGGAGAGAGAGAAAGCGCGGATAAGAGAGGAGTATGAA
GAGAAAATCAGAAAGCTGGAAGATAAAGTGGAGCAGGAAAAGAGAAAGAAGCAAATGGAG
AAGAAACTAGCAGAACAGGAGGCTCACTATGCTGTAAGGCAGCAAAGGGCAAGAACGGAA
GTGGAGAGTAAGGATGGGATACTTGAATTAATCATGACAGCGTTACAGATTGCTTCCTTT
ATTTTGTTACGTCTGTTCGCGGAAGATTAA
Protein Properties
Number of Residues 329
Molecular Weight 37533.5
Theoretical pI 7.97
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>GTPase IMAP family member 4
MAAQYGSMSFNPSTPGASYGPGRQEPRNSQLRIVLVGKTGAGKSATGNSILGRKVFHSGT
AAKSITKKCEKRSSSWKETELVVVDTPGIFDTEVPNAETSKEIIRCILLTSPGPHALLLV
VPLGRYTEEEHKATEKILKMFGERARSFMILIFTRKDDLGDTNLHDYLREAPEDIQDLMD
IFGDRYCALNNKATGAEQEAQRAQLLGLIQRVVRENKEGCYTNRMYQRAEEEIQKQTQAM
QELHRVELEREKARIREEYEEKIRKLEDKVEQEKRKKQMEKKLAEQEAHYAVRQQRARTE
VESKDGILELIMTALQIASFILLRLFAED
GenBank ID Protein 27462082
UniProtKB/Swiss-Prot ID Q9NUV9
UniProtKB/Swiss-Prot Entry Name GIMA4_HUMAN
PDB IDs Not Available
GenBank Gene ID AF117333
GeneCard ID GIMAP4
GenAtlas ID GIMAP4
HGNC ID HGNC:21872
References
General References
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  2. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
  3. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M: Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science. 2009 Aug 14;325(5942):834-40. doi: 10.1126/science.1175371. Epub 2009 Jul 16. [PubMed:19608861 ]
  4. Cambot M, Aresta S, Kahn-Perles B, de Gunzburg J, Romeo PH: Human immune associated nucleotide 1: a member of a new guanosine triphosphatase family expressed in resting T and B cells. Blood. 2002 May 1;99(9):3293-301. [PubMed:11964296 ]