Hmdb loader
Identification
HMDB Protein ID HMDBP08443
Secondary Accession Numbers
  • 14155
Name GTP-binding protein 10
Synonyms
  1. ObgH2
  2. Protein obg homolog 2
Gene Name GTPBP10
Protein Type Unknown
Biological Properties
General Function Involved in magnesium ion binding
Specific Function May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nuceleolar architecture is observed
Pathways Not Available
Reactions Not Available
GO Classification
Component
cell part
intracellular
Function
ion binding
cation binding
metal ion binding
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
magnesium ion binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
Cellular Location
  1. Nucleus
  2. nucleolus
  3. Chromosome
Gene Properties
Chromosome Location Chromosome:7
Locus 7q21.13
SNPs GTPBP10
Gene Sequence
>1164 bp
ATGGTGCATTGCAGTTGCGTGTTGTTCAGAAAGTATGGAAATTTCATCGATAAGCTAAGA
CTCTTCACCAGGGGAGGATCCGGTGGAATGGGTTATCCTCGTTTAGGTGGAGAAGGTGGA
AAAGGTGGTGATGTCTGGGTTGTAGCCCAGAACAGAATGACTTTAAAACAACTTAAAGAC
AGGTATCCTCGGAAACGGTTTGTGGCTGGAGTAGGAGCAAACAGCAAAATTAGTGCACTG
AAAGGCTCCAAAGGAAAAGACTGTGAAATCCCTGTGCCTGTGGGTATTTCAGTAACTGAT
GAAAATGGTAAAATTATAGGAGAACTCAATAAAGAAAATGACAGAATTTTGGTAGCTCAA
GGAGGTCTTGGTGGTAAATTACTTACAAATTTCTTACCATTGAAAGGCCAGAAACGAATA
ATTCACCTTGATCTAAAACTTATAGCTGATGTAGGCCTAGTAGGATTCCCAAATGCTGGA
AAATCCTCTTTGCTAAGTTGTGTTTCTCATGCAAAACCTGCAATTGCAGATTACGCATTT
ACAACATTAAAGCCTGAACTTGGAAAGATAATGTACAGTGATTTCAAACAGATATCAGTA
GCTGATCTTCCGGGTTTAATAGAAGGAGCACATATGAACAAAGGAATGGGCCACAAATTC
CTCAAGCATATAGAAAGAACTAGACAACTACTTTTTGTTGTTGATATTTCTGGATTTCAG
CTTTCTTCTCACACTCAATACAGGACAGCTTTTGAAACCATAATACTGCTTACAAAAGAG
TTGGAATTGTACAAAGAGGAACTTCAGACAAAACCTGCACTCTTGGCAGTTAATAAAATG
GACTTGCCAGATGCCCAAGATAAGTTCCATGAATTGATGAGCCAGCTCCAGAATCCTAAA
GATTTTCTGCATTTATTTGAAAAAAACATGATTCCAGAGAGGACTGTAGAGTTCCAACAT
ATCATCCCCATATCTGCAGTTACTGGAGAAGGAATCGAAGAATTAAAGAATTGTATAAGA
AAGTCACTGGATGAACAGGCCAACCAGGAAAATGATGCACTTCATAAGAAACAGTTGCTT
AATTTGTGGATTTCTGATACAATGTCTTCTACTGAGCCACCATCAAAGCATGCTGTTACT
ACTTCCAAAATGGATATAATTTAA
Protein Properties
Number of Residues 387
Molecular Weight 42932.6
Theoretical pI 9.55
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>GTP-binding protein 10
MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKD
RYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIGELNKENDRILVAQ
GGLGGKLLTNFLPLKGQKRIIHLDLKLIADVGLVGFPNAGKSSLLSCVSHAKPAIADYAF
TTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQ
LSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPK
DFLHLFEKNMIPERTVEFQHIIPISAVTGEGIEELKNCIRKSLDEQANQENDALHKKQLL
NLWISDTMSSTEPPSKHAVTTSKMDII
GenBank ID Protein 111955139
UniProtKB/Swiss-Prot ID A4D1E9
UniProtKB/Swiss-Prot Entry Name GTPBA_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_033107.2
GeneCard ID GTPBP10
GenAtlas ID GTPBP10
HGNC ID HGNC:25106
References
General References
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