Hmdb loader
Identification
HMDB Protein ID HMDBP08523
Secondary Accession Numbers
  • 14235
Name Ras and EF-hand domain-containing protein
Synonyms
  1. Ras-related protein Rab-45
Gene Name RASEF
Protein Type Unknown
Biological Properties
General Function Involved in calcium ion binding
Specific Function Binds predominantly GDP, and also GTP
Pathways Not Available
Reactions Not Available
GO Classification
Function
ion binding
cation binding
metal ion binding
purine nucleotide binding
binding
nucleotide binding
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
calcium ion binding
Process
establishment of localization
transport
protein transport
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
Cellular Location
  1. Cytoplasm
  2. perinuclear region
Gene Properties
Chromosome Location Chromosome:9
Locus 9q21.32
SNPs RASEF
Gene Sequence
>2223 bp
ATGGAGGCGGATGGGGACGGAGAGGAGCTGGCCCGGCTGCGCTCAGTCTTCGCCGCCTGC
GACGCGAACCGCTCGGGGCGCCTGGAGCGCGAGGAGTTCCGGGCACTGTGCACGGAGCTG
CGGGTGCGGCCGGCCGACGCCGAGGCAGTATTCCAGCGGCTGGACGCCGACCGTGACGGC
GCCATCACCTTCCAGGAGTTCGCGCGTGGCTTCCTCGGGTCCCTCCGCGGGGGGCGGCGC
CGGGACTGGGGTCCTCTGGATCCCGCGCCCGCCGTGTCTGAGGCGGGGCCGGAGACACAC
GACAGCGAGGAGGACGAAGGCGACGAGGACGCGGCGGCGGCGCTGGCCACCTCGTGCGGC
CCGGCGAGTCCCGGCCGGGCTTGGCAGGATTTCCAGGCGCGACTTGGGGACGAAGCCAAG
TTCATTCCCAGAGAAGAGCAAGTTAGTACCTTGTACCAAAACATCAACCTTGTGGAGCCA
AGATTAATTCAGCCATATGAACATGTTATAAAGAACTTCATCCGTGAGATCAGACTTCAA
AGCACAGAAATGGAAAATTTGGCCATTGCGGTGAAGAGAGCCCAGGACAAGGCAGCTATG
CAGTTGAGTGAGTTGGAAGAGGAAATGGATCAGAGGATTCAGGCTGCAGAACATAAGACA
CGGAAAGACGAAAAACGCAAAGCTGAGGAAGCCCTCAGTGACCTCAGACGTCAGTATGAA
ACTGAAGTAGGAGATCTGCAGGTGACCATTAAAAAGCTAAGAAAGCTCGAAGAACAATCA
AAACGCGTAAGTCAAAAGGAAGATGTGGCTGCATTGAAAAAACAAATTTATGATTTATCA
ATGGAAAACCAGAAAGTTAAGAAAGACCTTTTAGAAGCACAGACAAACATAGCCTTTCTT
CAGAGTGAGTTAGATGCTTTGAAAAGTGATTATGCTGATCAGAGTCTGAATACTGAAAGG
GATCTGGAAATAATCCGAGCATACACAGAAGATCGAAATAGTCTTGAGAGGCAAATTGAA
ATACTCCAAACAGCTAACCGGAAGCTACATGACAGTAATGATGGCCTTAGAAGTGCCCTT
GAAAACAGTTATAGCAAGTTCAACAGATCTTTGCATATAAATAATATCTCACCAGGGAAT
ACAATTTCTAGAAGCAGTCCCAAATTCATTGGTCATTCCCCTCAACCTCTAGGCTATGAC
AGGTCATCCCGCTCTTCCTATGTGGATGAGGACTGTGACTCCCTGGCCCTCTGTGATCCT
CTGCAGAGGACAAATTGTGAAGTTGACAGCCTGCCTGAAAGCTGCTTCGACAGCGGCTTG
TCTACCTTGAGAGATCCCAATGAGTATGACTCAGAAGTGGAATACAAGCACCAGAGGGGA
TTTCAGAGGTCACACGGGGTGCAGGAGAGCTTTGGAGGTGATGCTTCAGACACAGATGTT
CCTGACATAAGGGATGAAGAGACATTTGGTTTAGAAGATGTGGCTTCCGTCTTAGACTGG
AAGCCCCAAGGGTCTGTTAGTGAAGGCAGCATTGTTAGTTCATCAAGAAAGCCCATCTCA
GCACTCTCGCCCCAGACAGACCTGGTAGATGACAACGCTAAATCTTTTAGCTCACAGAAG
GCTTACAAGATTGTACTTGCTGGGGACGCTGCAGTGGGGAAGTCTAGTTTCCTCATGAGA
CTTTGCAAGAATGAATTTCGAGAAAATATAAGCGCCACCCTGGGAGTTGATTTCCAAATG
AAAACCCTCATTGTGGATGGAGAACGAACAGTTCTGCAGCTCTGGGATACAGCTGGTCAG
GAGAGATTCAGAAGTATTGCCAAGTCTTACTTCAGAAAGGCAGATGGTGTTTTGCTGCTG
TATGATGTTACATGTGAGAAAAGCTTTCTTAACATACGAGAATGGGTAGATATGATTGAG
GATGCAGCCCATGAGACTGTTCCCATTATGCTGGTAGGAAACAAGGCTGACATTCGTGAC
ACTGCTGCTACAGAGGGACAAAAATGTGTCCCAGGGCACTTTGGAGAGAAACTGGCCATG
ACGTATGGGGCATTATTCTGTGAAACAAGTGCCAAAGATGGTTCTAACATAGTGGAGGCT
GTTCTGCACCTTGCTCGAGAAGTGAAAAAGAGAACTGACAAGGATGACAGCAGATCCATT
ACCAATCTAACCGGGACCAATTCCAAAAAGTCACCACAGATGAAGAATTGTTGCAATGGC
TAA
Protein Properties
Number of Residues 740
Molecular Weight 82878.3
Theoretical pI 4.73
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Ras and EF-hand domain-containing protein
MEADGDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDG
AITFQEFARGFLGSLRGGRRRDWGPLDPAPAVSEAGPETHDSEEDEGDEDAAAALATSCG
PASPGRAWQDFQARLGDEAKFIPREEQVSTLYQNINLVEPRLIQPYEHVIKNFIREIRLQ
STEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYE
TEVGDLQVTIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQTNIAFL
QSELDALKSDYADQSLNTERDLEIIRAYTEDRNSLERQIEILQTANRKLHDSNDGLRSAL
ENSYSKFNRSLHINNISPGNTISRSSPKFIGHSPQPLGYDRSSRSSYVDEDCDSLALCDP
LQRTNCEVDSLPESCFDSGLSTLRDPNEYDSEVEYKHQRGFQRSHGVQESFGGDASDTDV
PDIRDEETFGLEDVASVLDWKPQGSVSEGSIVSSSRKPISALSPQTDLVDDNAKSFSSQK
AYKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQ
ERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRD
TAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSI
TNLTGTNSKKSPQMKNCCNG
GenBank ID Protein 40255119
UniProtKB/Swiss-Prot ID Q8IZ41
UniProtKB/Swiss-Prot Entry Name RASEF_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_152573.2
GeneCard ID RASEF
GenAtlas ID RASEF
HGNC ID HGNC:26464
References
General References
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