Hmdb loader
Identification
HMDB Protein ID HMDBP08524
Secondary Accession Numbers
  • 14236
Name Ras association domain-containing protein 2
Synonyms Not Available
Gene Name RASSF2
Protein Type Unknown
Biological Properties
General Function Involved in signal transduction
Specific Function Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest
Pathways Not Available
Reactions Not Available
GO Classification
Function
binding
protein binding
Process
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
Cellular Location
  1. Nucleus
Gene Properties
Chromosome Location Chromosome:2
Locus 20p13
SNPs RASSF2
Gene Sequence
>981 bp
ATGGACTACAGCCACCAAACGTCCCTAGTCCCATGTGGACAAGATAAATACATTTCCAAA
AATGAACTTCTCTTGCATCTGAAGACCTACAACTTGTACTATGAAGGCCAGAATTTACAG
CTCCGGCACCGGGAGGAAGAAGACGAGTTCATTGTGGAGGGGCTCCTGAACATCTCCTGG
GGCCTGCGCCGGCCCATTCGCCTGCAGATGCAGGATGACAACGAACGCATTCGACCCCCT
CCATCCTCCTCCTCCTGGCACTCTGGCTGTAACCTGGGGGCTCAGGGAACCACTCTGAAG
CCCCTGACTGTGCCCAAAGTTCAGATCTCAGAGGTGGATGCCCCGCCGGAGGGTGACCAG
ATGCCAAGCTCCACAGACTCCAGGGGCCTGAAGCCCCTGCAGGAGGACACCCCACAGCTG
ATGCGCACACGCAGTGATGTTGGGGTGCGTCGCCGTGGCAATGTGAGGACGCCTAGTGAC
CAGCGGCGAATCAGATGCCACCGCTTCTCCATCAACGGCCATTTCTACAACCATAAGACA
TCCGTGTTCACACCAGCCTATGGCTCTGTCACCAACGTCCGCATCAACAGCACCATGACC
ACCCCACAGGTCCTGAAGCTGCTGCTCAACAAATTTAAGATTGAGAATTCAGCAGAGGAG
TTTGCCTTGTACGTGGTCCATACGAGTGGTGAGAAACAGAAGCTGAAGGCCACCGATTAC
CCGCTGATTGCCCGAATCCTCCAGGGCCCATGTGAGCAGATCTCCCAAGTGTTCCTAATG
GAGAAGGACCAGGTGGAGGAAGTCACCTACGACGTGGCCCAGTATATAAAGTTCGAGATG
CCGGTACTTAAAAGCTTCATTCAGAAGCTCCAGGAGGAAGAAGATCGGGAAGTAAAGAAG
CTGATGCGCAAGTACACCGTGCTCCGGCTAATGATTCGACAGAGGCTGGAGGAGATAGCC
GAGACCCCAGCAACAATCTGA
Protein Properties
Number of Residues 326
Molecular Weight 37789.9
Theoretical pI 9.17
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Ras association domain-containing protein 2
MDYSHQTSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISW
GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQ
MPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFSINGHFYNHKT
SVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDY
PLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKK
LMRKYTVLRLMIRQRLEEIAETPATI
GenBank ID Protein 62896859
UniProtKB/Swiss-Prot ID P50749
UniProtKB/Swiss-Prot Entry Name RASF2_HUMAN
PDB IDs Not Available
GenBank Gene ID AK222650
GeneCard ID RASSF2
GenAtlas ID RASSF2
HGNC ID HGNC:9883
References
General References
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