Hmdb loader
Identification
HMDB Protein ID HMDBP08567
Secondary Accession Numbers
  • 14281
Name Ras-related GTP-binding protein C
Synonyms
  1. GTPase-interacting protein 2
  2. Rag C
  3. RagC
  4. TIB929
Gene Name RRAGC
Protein Type Unknown
Biological Properties
General Function Involved in GTP binding
Specific Function Has guanine nucleotide-binding activity but weak intrinsic GTPase activity
Pathways Not Available
Reactions Not Available
GO Classification
Component
cell part
intracellular part
cytoplasm
organelle
membrane-bounded organelle
intracellular membrane-bounded organelle
nucleus
Function
purine nucleotide binding
binding
nucleotide binding
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
Cellular Location
  1. Nucleus
  2. Cytoplasm
Gene Properties
Chromosome Location Chromosome:1
Locus 1p34
SNPs RRAGC
Gene Sequence
>1200 bp
ATGTCCCTGCAGTACGGGGCGGAGGAGACGCCCCTCGCCGGCAGTTACGGCGCGGCCGAT
TCGTTTCCAAAGGACTTCGGCTACGGCGTGGAGGAGGAGGAAGAGGAGGCGGCGGCGGCG
GGCGGAGGGGTTGGGGCAGGGGCAGGCGGTGGCTGTGGTCCGGGGGGCGCTGACAGCTCC
AAGCCGAGGATTCTGCTCATGGGACTCCGGCGCAGCGGCAAGTCCTCCATCCAGAAGGTG
GTGTTTCATAAGATGTCACCCAACGAGACCCTCTTTTTGGAAAGTACCAACAAGATTTAT
AAGGATGACATTTCCAATAGCTCCTTTGTGAATTTCCAGATATGGGATTTTCCTGGGCAA
ATGGACTTTTTTGACCCAACCTTTGACTATGAGATGATCTTCAGGGGAACAGGAGCATTG
ATATACGTCATTGACGCACAGGATGACTACATGGAGGCTTTAACAAGACTTCACATTACT
GTTTCTAAAGCCTACAAAGTTAACCCAGACATGAATTTTGAGGTTTTTATTCACAAAGTT
GATGGTCTGTCTGATGATCACAAAATAGAAACACAGAGGGACATTCATCAAAGGGCCAAT
GATGACCTTGCAGATGCTGGGCTAGAAAAACTCCATCTTAGCTTTTATCTGACTAGTATC
TATGACCATTCAATATTTGAAGCCTTTAGTAAGGTGGTGCAGAAACTCATTCCACAACTG
CCGACCTTGGAAAACCTATTAAATATCTTTATATCAAATTCAGGTATTGAAAAAGCTTTT
CTCTTTGATGTTGTCAGCAAAATCTACATTGCAACAGACAGTTCCCCTGTGGATATGCAA
TCTTATGAACTTTGCTGTGACATGATCGATGTTGTAATTGATGTGTCTTGTATATATGGG
TTAAAGGAAGATGGAAGTGGAAGTGCTTATGACAAAGAATCTATGGCAATTATCAAGCTG
AATAATACAACTGTCCTTTATTTAAAGGAGGTGACTAAATTTTTGGCACTGGTCTGCATT
CTAAGGGAAGAAAGCTTTGAAAGAAAAGGTTTAATAGACTACAACTTCCACTGTTTCCGA
AAAGCTATTCATGAGGTTTTTGAGGTGGGTGTGACTTCTCACAGGAGCTGTGGTCACCAG
ACTAGTGCCTCCAGTCTGAAAGCGCTGACACACAATGGCACGCCACGAAACGCCATCTAG
Protein Properties
Number of Residues 399
Molecular Weight 44223.5
Theoretical pI 4.72
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Ras-related GTP-binding protein C
MSLQYGAEETPLAGSYGAADSFPKDFGYGVEEEEEEAAAAGGGVGAGAGGGCGPGGADSS
KPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQ
MDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVFIHKV
DGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLIPQL
PTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSCIYG
LKEDGSGSAYDKESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERKGLIDYNFHCFR
KAIHEVFEVGVTSHRSCGHQTSASSLKALTHNGTPRNAI
GenBank ID Protein 11181618
UniProtKB/Swiss-Prot ID Q9HB90
UniProtKB/Swiss-Prot Entry Name RRAGC_HUMAN
PDB IDs Not Available
GenBank Gene ID AF272035
GeneCard ID RRAGC
GenAtlas ID RRAGC
HGNC ID HGNC:19902
References
General References
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  4. Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. Sci Signal. 2009 Aug 18;2(84):ra46. doi: 10.1126/scisignal.2000007. [PubMed:19690332 ]
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  6. Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T: A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D. J Biol Chem. 2004 Feb 27;279(9):8343-50. Epub 2003 Dec 4. [PubMed:14660641 ]
  7. Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T: Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B. J Biol Chem. 2001 Mar 9;276(10):7246-57. Epub 2000 Nov 9. [PubMed:11073942 ]
  8. Horwitz MS: Adenovirus immunoregulatory genes and their cellular targets. Virology. 2001 Jan 5;279(1):1-8. [PubMed:11145883 ]