Hmdb loader
Identification
HMDB Protein ID HMDBP08590
Secondary Accession Numbers
  • 14305
Name Synaptotagmin-like protein 1
Synonyms
  1. Exophilin-7
  2. Protein JFC1
Gene Name SYTL1
Protein Type Unknown
Biological Properties
General Function Involved in Rab GTPase binding
Specific Function May play a role in vesicle trafficking. Binds phosphatidylinositol 3,4,5-triphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes
Pathways Not Available
Reactions Not Available
GO Classification
Function
small gtpase regulator activity
enzyme regulator activity
rab gtpase binding
nucleoside-triphosphatase regulator activity
gtpase regulator activity
Process
establishment of localization
transport
protein transport
intracellular protein transport
Cellular Location
  1. Cell membrane
  2. Peripheral membrane protein
  3. Cytoplasmic side
Gene Properties
Chromosome Location Chromosome:1
Locus 1p36.11
SNPs SYTL1
Gene Sequence
>1689 bp
ATGCCCCAGAGGGGCCACCCATCGCAAGAGGGGCTTTGGGCTCTGCCCTCCCTCCCCATG
GCGCATGGGCCAAAGCCTGAGACTGAAGGACTGTTGGACCTCAGCTTCCTGACAGAGGAG
GAGCAGGAGGCCATTGCTGGCGTCCTCCAACGAGATGCCCGCCTGCGCCAGCTGGAGGAG
GGGCGGGTCAGCAAGCTCCGGGCCTCAGTGGCAGACCCTGGGCAGCTGAAGATCCTGACA
GGGGACTGGTTCCAGGAAGCACGCTCCCAGCGGCACCACAATGCCCACTTCGGCTCTGAC
CTTGTCCGAGCGTCTATGCGCAGGAAGAAGAGCACCAGGGGAGACCAGGCTCCAGGCCAC
GACAGGGAGGCTGAGGCTGCTGTGAAAGAGAAGGAAGAGGGGCCAGAGCCCAGGCTCACC
ATTGATGAGGCCCCTCAGGAGAGGCTCAGGGAGACTGAGGGACCTGATTTCCCATCGCCT
TCTGTCCCCCTAAAGGCTTCAGATCCTGAGGAGGCGTCCCAGGCCCAGGAAGATCCTGGC
CAAGGAGACCAACAGGTCTGTGCCGAGGAGGCTGACCCGGAGCTGGAGCCCGCGTCGGGG
GGAGAGCAGGAGCCGCGGCCCCAGCAAGCCCAGACCAAGGCCGCGTCCCAGATCCTGGAG
AATGGGGAGGAGGCCCCGGGGCCCGACCCCTCTCTCGACCGCATGCTCAGCAGCAGCTCC
TCGGTGTCCAGCCTTAACTCCTCCACGCTGAGCGGCAGCCAGATGAGCCTGTCAGGCGAC
GCGGAGGCGGTGCAGGTCCGCGGCTCCGTGCACTTCGCGCTGCACTACGAGCCGGGCGCC
GCCGAGCTGCGCGTGCACGTGATCCAGTGCCAGGGCCTGGCCGCCGCCCGGCGCCGCCGC
TCGGACCCCTACGTCAAAAGCTACCTCCTCCCGGATAAGCAGAGCAAGCGCAAGACGGCG
GTGAAGAAACGGAATCTGAATCCGGTTTTCAACGAGACTCTCCGGTACTCCGTCCCGCAG
GCCGAGCTTCAGGGCCGCGTGCTGAGCCTGTCTGTGTGGCACCGCGAAAGCCTGGGTCGC
AACATCTTTCTGGGCGAAGTTGAAGTGCCCCTGGACACGTGGGACTGGGGCTCTGAGCCC
ACCTGGCTCCCCCTGCAGCCCCGGGTCCCACCCTCTCCCGACGACCTTCCGAGCCGCGGG
TTACTCGCCCTGTCCCTCAAGTACGTCCCCGCCGGCTCCGAGGGCGCAGGACTGCCCCCG
AGCGGGGAGCTGCACTTCTGGGTGAAGGAGGCTCGGGACCTCCTGCCGCTGCGGGCAGGA
TCCCTGGACACTTACGTACAATGCTTCGTGCTGCCTGATGACAGCCAGGCCAGCCGCCAG
CGTACAAGGGTTGTGCGACGCAGCCTCAGCCCTGTGTTCAATCACACCATGGTGTACGAT
GGCTTTGGGCCTGCTGACCTGCGCCAGGCTTGTGCCGAGCTCTCCCTCTGGGACCATGGG
GCCCTGGCCAACCGCCAGCTGGGGGGCACACGCCTCAGCCTGGGCACCGGCAGCAGCTAT
GGGCTGCAGGTGCCCTGGATGGATTCCACACCTGAGGAGAAGCAGCTGTGGCAAGCCCTC
CTGGAGCAGCCGTGCGAATGGGTGGATGGCCTTCTACCCCTCAGAACCAACCTGGCCCCC
AGGACGTAG
Protein Properties
Number of Residues 562
Molecular Weight 61856.5
Theoretical pI 5.16
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Synaptotagmin-like protein 1
MPQRGHPSQEGLWALPSLPMAHGPKPETEGLLDLSFLTEEEQEAIAGVLQRDARLRQLEE
GRVSKLRASVADPGQLKILTGDWFQEARSQRHHNAHFGSDLVRASMRRKKSTRGDQAPGH
DREAEAAVKEKEEGPEPRLTIDEAPQERLRETEGPDFPSPSVPLKASDPEEASQAQEDPG
QGDQQVCAEEADPELEPASGGEQEPRPQQAQTKAASQILENGEEAPGPDPSLDRMLSSSS
SVSSLNSSTLSGSQMSLSGDAEAVQVRGSVHFALHYEPGAAELRVHVIQCQGLAAARRRR
SDPYVKSYLLPDKQSKRKTAVKKRNLNPVFNETLRYSVPQAELQGRVLSLSVWHRESLGR
NIFLGEVEVPLDTWDWGSEPTWLPLQPRVPPSPDDLPSRGLLALSLKYVPAGSEGAGLPP
SGELHFWVKEARDLLPLRAGSLDTYVQCFVLPDDSQASRQRTRVVRRSLSPVFNHTMVYD
GFGPADLRQACAELSLWDHGALANRQLGGTRLSLGTGSSYGLQVPWMDSTPEEKQLWQAL
LEQPCEWVDGLLPLRTNLAPRT
GenBank ID Protein 300863107
UniProtKB/Swiss-Prot ID Q8IYJ3
UniProtKB/Swiss-Prot Entry Name SYTL1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001193308.1
GeneCard ID SYTL1
GenAtlas ID SYTL1
HGNC ID HGNC:15584
References
General References
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