Showing Protein Triple functional domain protein (HMDBP08613)

• 14328

1. PTPRF-interacting protein

1. Cytoplasm

>9294 bp
ATGAGCGGCAGCAGCGGCGGAGCCGCCGCCCCCGCCGCGTCCTCCGGCCCCGCCGCGGCG
GCCAGCGCGGCTGGCTCGGGCTGCGGGGGCGGTGCCGGCGAGGGGGCAGAGGAGGCGGCC
AAGGACCTGGCCGACATCGCGGCCTTCTTCCGATCCGGGTTTCGAAAAAACGATGAAATG
AAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGA
GATAAACGTGGAGGTCCCATTTTAACGTTTCCGGCCCGCAGCAATCATGACAGAATACGA
CAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCCTGTATTCCCAGCGAGGAGGTCTGC
AAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCC
CTTCTGAAGATCCTGCAGGAGTCCTTCCCCTGCTGCATCCATGTGGCCCTGATCATCAAG
CCAGACAACTTCTGGCAGAAACAGAGGACTAATTTTGGCAGTTCTAAATTTGAATTTGAG
ACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCT
GAGTTTGATGGCTGCCTGGAATACAACCACGAAGAATGGATTGAAATCAGAGTTGCTTTT
GAAGACTACATTAGCAATGCCACCCACATGCTGTCTCGGCTGGAGGAACTTCAGGACATC
CTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACAT
TCTCAGCTGAAGAAGAAGGTGATTAAGGCCCCCATCGAGGACCTGGATTTGGAGGGACAG
AAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTTCCCAAAAAGAACTCAGGCTCAGGC
AATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCG
ACACGGCAGCATCTGCACCAGATGTGGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTC
CAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATGTTTGACTGGATCACACACAACAAA
GGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTT
CAGACGCAGCACAATCACTTTGCCATGAACTGTATGAACGTGTATGTAAATATAAACCGC
ATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGCCACTATGCCTCGCAGCAGATCAGG
CAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGG
AGCACCTTGCTGGACATGTCCTCCATTTTCCACCAGAAGGCCGAAAAGTATATGAGCAAC
GTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGACCTTCCCTCAGAGCTGCAGGACCTA
GAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAG
GTCAGCCAAGATGGGAAGTCGCTCCTTGACAAGCTCCAGCGGCCCTTGACTCCCGGCAGC
TCCGATTCCCTGACAGCCTCTGCCAACTACTCCAAGGCCGTGCACCATGTCCTGGATGTC
ATCCACGAGGTGCTGCACCACCAGCGGCAGCTGGAGAACATCTGGCAACACCGCAAGGTC
CGGCTGCATCAGAGGCTGCAGCTGTGTGTTTTCCAGCAGGACGTTCAGCAGGTGCTAGAC
TGGATCGAGAACCACGGAGAAGCATTTCTGAGCAAACATACAGGTGTGGGGAAATCTCTT
CATCGGGCCAGAGCATTGCAGAAACGTCATGAAGATTTTGAAGAAGTGGCACAGAACACA
TACACCAATGCGGATAAATTACTGGAAGCAGCAGAACAGCTGGCTCAGACTGGGGAATGT
GACCCCGAAGAGATTTATCAGGCTGCCCATCAGCTGGAAGACCGGATTCAAGATTTCGTT
CGGCGTGTTGAGCAGCGAAAGATCCTACTGGACATGTCAGTGTCCTTTCACACCCATGTG
AAAGAGCTGTGGACGTGGCTGGAGGAGCTGCAGAAGGAGCTGCTGGACGACGTGTATGCC
GAGTCGGTGGAGGCCGTGCAGGACCTCATCAAGCGCTTTGGCCAGCAGCAGCAGACCACC
CTGCAGGTGACTGTCAACGTGATCAAGGAAGGGGAGGACCTCATCCAGCAGCTCAGGGAC
TCTGCCATCTCCAGTAACAAGACCCCCCACAACAGCTCCATCAACCACATTGAGACGGTG
CTGCAGCAGCTGGACGAGGCGCAGTCGCAGATGGAGGAGCTCTTCCAGGAGCGCAAGATC
AAGCTGGAGCTCTTCCTGCAGCTGCGCATCTTCGAGAGGGACGCCATCGACATTATCTCA
GACCTCGAGTCTTGGAATGATGAGCTTTCTCAGCAAATGAATGACTTCGACACAGAAGAT
CTCACGATTGCAGAGCAGCGCCTCCAGCACCATGCAGACAAAGCCTTGACCATGAACAAC
TTGACTTTTGACGTCATCCACCAAGGGCAAGATCTTCTGCAGTATGTCAATGAGGTCCAG
GCCTCTGGTGTGGAGCTGCTGTGTGATAGAGATGTAGACATGGCAACTCGGGTCCAGGAC
CTGCTGGAGTTTCTTCATGAAAAACAGCAGGAATTGGATTTAGCCGCAGAGCAGCATCGG
AAACACCTGGAGCAGTGCGTGCAGCTGCGCCACCTGCAGGCAGAAGTGAAACAGGTGCTG
GGTTGGATCCGCAACGGAGAGTCCATGTTAAATGCCGGACTTATCACAGCCAGCTCGTTA
CAAGAGGCAGAGCAGCTCCAGCGAGAGCACGAGCAGTTCCAGCATGCCATTGAGAAAACA
CATCAGAGCGCGCTGCAGGTGCAGCAGAAGGCAGAAGCCATGCTACAGGCCAACCACTAC
GACATGGACATGATCCGGGACTGCGCCGAGAAGGTGGCGTCTCACTGGCAACAGCTCATG
CTCAAGATGGAAGATCGCCTCAAGCTCGTCAACGCCTCTGTCGCTTTCTACAAAACCTCA
GAGCAGGTCTGCAGCGTCCTCGAGAGCCTGGAACAGGAGTACAAGAGAGAAGAAGACTGG
TGTGGCGGGGCGGATAAGCTGGGCCCAAACTCTGAGACGGACCACGTGACGCCCATGATC
AGCAAGCACCTGGAGCAGAAGGAGGCATTCCTGAAGGCTTGCACCCTTGCTCGGAGGAAT
GCAGACGTCTTCCTGAAATACCTGCACAGGAACAGCGTGAACATGCCAGGAATGGTGACG
CACATCAAAGCTCCTGAACAGCAAGTGAAAAATATCTTGAATGAACTCTTCCAACGGGAG
AACAGGGTATTGCATTACTGGACCATGAGGAAGAGACGGCTGGACCAGTGTCAGCAGTAC
GTGGTCTTTGAGAGGAGTGCCAAGCAGGCTTTGGAATGGATCCATGACAATGGCGAGTTC
TACCTTTCCACACACACCTCCACGGGCTCCAGTATACAGCACACCCAGGAGCTCCTGAAA
GAGCACGAGGAGTTCCAGATAACTGCAAAGCAAACCAAAGAGAGAGTGAAGCTATTGATA
CAGCTGGCTGATGGCTTTTGTGAAAAAGGGCATGCCCATGCGGCAGAGATAAAAAAATGT
GTTACTGCTGTGGATAAGAGGTACAGAGATTTCTCTCTGCGGATGGAGAAGTACAGGACC
TCTTTGGAAAAAGCCCTGGGGATTTCTTCAGATTCCAACAAATCGAGTAAAAGTCTCCAG
CTAGATATCATTCCAGCCAGTATCCCTGGCTCAGAGGTGAAACTTCGAGATGCTGCTCAT
GAACTTAATGAAGAGAAGCGGAAATCTGCCCGCAGGAAAGAGTTCATAATGGCTGAGCTC
ATTCAAACTGAAAAGGCTTATGTAAGAGACCTCCGGGAATGTATGGATACGTACCTGTGG
GAAATGACCAGTGGCGTGGAAGAGATTCCACCTGGCATTGTAAACAAAGAACTCATCATC
TTCGGAAACATGCAAGAAATCTACGAATTTCATAATAACATATTCCTAAAGGAGCTGGAA
AAATATGAACAGTTGCCAGAGGATGTTGGACATTGTTTTGTTACTTGGGCAGACAAGTTT
CAGATGTATGTCACATATTGCAAAAATAAGCCTGATTCTACTCAGCTGATATTGGAACAT
GCAGGGTCCTATTTTGACGAGATACAGCAGCGACATGGATTAGCCAATTCCATTTCTTCC
TACCTTATTAAACCAGTTCAGCGAATAACGAAGTATCAGCTCCTTTTAAAAGAGCTGCTG
ACGTGCTGTGAGGAAGGAAAGGGAGAGATTAAAGATGGCCTGGAGGTGATGCTCAGCGTG
CCGAAGCGAGCCAATGATGCCATGCACCTCAGCATGCTGGAAGGGTTTGATGAAAACATT
GAGTCTCAGGGAGAACTCATCCTACAGGAATCCTTCCAAGTGTGGGACCCAAAAACCTTA
ATTCGAAAGGGTCGAGAACGGCATCTCTTCCTTTTTGAAATGTCCTTAGTATTTAGTAAA
GAAGTGAAAGATTCCAGTGGGAGAAGCAAGTACCTTTATAAAAGCAAATTGTTTACCTCA
GAGTTGGGTGTCACAGAACATGTTGAAGGAGACCCTTGCAAATTTGCACTGTGGGTGGGG
AGAACACCAACTTCAGATAATAAAATTGTCCTTAAGGCTTCCAGCATAGAGAACAAGCAG
GACTGGATAAAGCATATCCGCGAAGTCATCCAGGAGCGGACGATCCACCTGAAGGGAGCC
CTGAAGGAGCCCATTCACATCCCTAAGACCGCTCCCGCCACAAGACAGAAGGGAAGGAGG
GATGGAGAGGATCTGGACAGCCAAGGAGACGGCAGCAGCCAGCCTGATACGATTTCCATC
GCCTCACGGACGTCTCAGAACACGCTGGACAGCGATAAGCTCTCTGGTGGCTGTGAGCTG
ACAGTGGTGATCCATGACTTCACCGCTTGCAACAGCAACGAGCTGACCATCCGACGGGGC
CAGACCGTGGAAGTTCTGGAGCGGCCGCATGACAAGCCTGACTGGTGTCTGGTGCGGACA
ACTGACCGCTCCCCAGCGGCAGAAGGCCTGGTCCCCTGTGGTTCACTGTGCATCGCCCAC
TCCAGAAGTAGCATGGAAATGGAGGGCATCTTCAACCACAAAGACTCGCTCTCCGTCTCC
AGCAATGACGCCAGTCCACCCGCATCCGTGGCTTCCCTCCAGCCCCACATGATCGGGGCC
CAGAGCTCGCCGGGCCCCAAGCGGCCGGGCAACACCCTGCGCAAGTGGCTCACCAGCCCC
GTGCGGCGGCTCAGCAGCGGCAAGGCCGACGGGCACGTGAAGAAGCTGGCGCACAAGCAC
AAGAAGAGCCGCGAGGTCCGCAAGAGCGCCGACGCCGGCTCGCAGAAGGACTCCGACGAC
AGTGCGGCCACCCCGCAGGACGAGACGGTCGAGGAGAGAGGCCGGAACGAGGGCCTGAGC
AGCGGTACTCTCTCCAAATCCTCCTCCTCGGGGATGCAGAGCTGTGGAGAAGAGGAAGGC
GAGGAGGGGGCCGACGCCGTGCCCCTGCCGCCACCCATGGCCATCCAGCAGCACAGCCTC
CTCCAGCCAGACTCACAGGATGACAAGGCCTCTTCTCGGTTATTAGTCCGCCCCACCAGC
TCCGAAACACCGAGTGCAGCCGAGCTCGTCAGTGCAATTGAGGAACTCGTGAAAAGCAAG
ATGGCACTGGAGGATCGCCCCAGCTCACTCCTTGTTGACCAGGGAGATAGTAGCAGCCCT
TCCTTCAACCCTTCGGATAATTCCCTTCTCTCTTCCTCCTCGCCCATTGATGAGATGGAA
GAAAGGAAATCCAGCTCTTTAAAGAGAAGACACTACGTTTTGCAAGAACTAGTGGAGACA
GAGCGTGACTATGTGCGGGACCTTGGCTATGTGGTTGAGGGCTACATGGCACTTATGAAA
GAAGATGGTGTTCCTGATGACATGAAAGGAAAAGACAAAATTGTGTTCGGCAACATCCAT
CAGATTTACGACTGGCACAGAGACTTTTTTTTAGGAGAGTTAGAGAAGTGCCTTGAAGAT
CCAGAAAAACTAGGATCCCTTTTTGTTAAACACGAGAGAAGGTTGCACATGTACATAGCT
TATTGTCAAAATAAACCAAAGTCTGAGCACATTGTCTCAGAATACATTGATACCTTTTTT
GAGGACTTAAAGCAGCGTCTTGGCCACAGGTTACAGCTCACAGATCTGTTGATCAAACCA
GTGCAGAGAATCATGAAGTATCAGCTGTTACTGAAGGACTTCCTCAAGTATTCCAAAAAG
GCCAGCCTGGATACATCAGAATTAGAGAGAGCTGTGGAAGTCATGTGCATAGTACCCAGG
CGGTGCAACGACATGATGAACGTGGGGCGGCTGCAAGGATTCGACGGGAAAATCGTTGCC
CAGGGTAAACTGCTCTTGCAGGACACATTCTTGGTCACAGACCAAGATGCAGGACTTCTG
CCTCGCTGCAGAGAGAGGCGCATCTTCCTCTTTGAGCAGATCGTCATATTCAGCGAACCA
CTTGATAAAAAGAAGGGCTTCTCCATGCCGGGATTCCTGTTTAAGAACAGTATCAAGGTG
AGTTGCCTTTGCCTGGAGGAAAATGTGGAAAATGATCCCTGTAAATTTGCTCTGACATCG
AGGACGGGTGACGTGGTAGAGACCTTCATTTTGCATTCATCTAGTCCAAGTGTCCGGCAA
ACTTGGATCCATGAAATCAACCAAATTTTAGAAAACCAGCGCAATTTTTTAAATGCCTTG
ACATCGCCAATCGAGTACCAGAGGAACCACAGCGGGGGCGGCGGCGGCGGCGGCAGCGGG
GGCAGCGGCGGGGGTGGGGGCAGCGGCGGCGGCGGGGCCCCCAGTGGCGGCAGCGGCCAC
AGTGGCGGCCCCAGCAGCTGCGGCGGCGCCCCCAGCACGAGCAGGAGCCGGCCCTCCCGG
ATCCCCCAGCCTGTCCGACACCACCCCCCCGTGCTGGTCTCCTCTGCAGCCTCGAGCCAG
GCAGAGGCAGACAAGATGTCAGGTACGTCCACCCCCGGGCCCTCCCTGCCTCCCCCTGGC
GCGGCCCCCGAGGCCGGCCCCAGCGCGCCCAGCAGGCGGCCCCCCGGCGCGGACGCCGAG
GGGTCCGAGCGAGAAGCGGAGCCGATCCCCAAGATGAAGGTGCTGGAGAGCCCCAGGAAA
GGCGCCGCGAACGCCTCGGGGTCGAGCCCAGACGCCCCCGCCAAGGACGCGCGCGCTAGC
CTGGGCACCCTGCCGCTTGGGAAGCCCCGGGCCGGGGCCGCTTCGCCGCTGAACTCGCCG
CTCTCCAGCGCGGTCCCTTCTCTCGGCAAGGAGCCCTTCCCCCCCAGCAGCCCCCTGCAG
AAGGGGGGCTCCTTCTGGAGCTCCATCCCCGCCTCCCCCGCCAGCCGACCCGGCTCCTTC
ACCTTCCCGGGGGACAGCGACTCCCTCCAGCGGCAGACACCCCGCCACGCGGCCCCTGGC
AAGGATACTGACCGCATGAGCACGTGCTCCTCGGCCAGCGAGCAGTCCGTGCAGTCCACC
CAGAGCAACGGGAGTGAAAGCAGCAGCAGTAGCAACATCTCCACCATGTTGGTGACACAC
GATTACACGGCAGTGAAGGAGGATGAGATCAACGTCTACCAAGGAGAGGTCGTTCAAATT
CTGGCCAGCAACCAGCAGAACATGTTTCTGGTGTTCCGAGCCGCCACTGACCAGTGCCCC
GCAGCTGAGGGCTGGATTCCAGGCTTTGTCCTGGGCCACACCAGTGCAGTCATCGTGGAG
AACCCGGACGGGACTCTCAAGAAGTCAACATCTTGGCACACAGCACTCCGTTTAAGGAAA
AAATCTGAGAAAAAAGATAAAGACGGCAAAAGGGAAGGCAAGTTAGAGAACGGTTATCGG
AAGTCACGGGAAGGACTCAGCAACAAGGTATCTGTGAAGCTTCTCAATCCCAACTACATT
TATGACGTTCCCCCAGAATTCGTCATTCCATTGAGTGAGGTCACGTGTGAGACAGGGGAG
ACCGTTGTTCTTAGATGTCGAGTCTGTGGCCGCCCCAAAGCCTCAATTACCTGGAAGGGC
CCTGAACACAACACCTTGAACAACGATGGTCACTACAGCATCTCCTACAGTGACCTGGGA
GAGGCCACGCTGAAGATTGTGGGCGTGACCACGGAAGATGACGGCATCTACACGTGCATC
GCTGTCAATGACATGGGTTCAGCCTCATCGTCGGCCAGCCTGAGGGTCCTAGGTCCAGGG
ATGGATGGGATCATGGTGACCTGGAAAGACAACTTTGACTCCTTCTACAGTGAAGTGGCT
GAGCTTGGCAGGGGCAGATTCTCTGTCGTTAAGAAATGTGATCAGAAAGGAACCAAGCGA
GCAGTGGCCACTAAGTTTGTGAACAAGAAGTTGATGAAGCGCGACCAGGTCACCCATGAG
CTTGGCATCCTGCAGAGCCTCCAGCACCCCCTGCTTGTCGGCCTCCTCGACACCTTTGAG
ACCCCCACCAGCTACATCCTGGTCTTAGAAATGGCTGACCAGGGTCGCCTCCTGGACTGC
GTGGTGCGATGGGGAAGCCTCACTGAAGGGAAGATCAGGGCGCACCTGGGGGAGGTTCTG
GAAGCTGTCCGGTACCTGCACAACTGCAGGATAGCACACCTGGACCTAAAGCCTGAGAAT
ATCCTGGTGGATGAGAGTTTAGCCAAGCCAACCATCAAACTGGCTGACTTTGGAGATGCT
GTTCAGCTCAACACGACCTACTACATCCACCAGTTACTGGGGAACCCTGAATTCGCAGCC
CCTGAAATCATCCTCGGGAACCCTGTCTCCCTGACCTCGGATACGTGGAGTGTTGGAGTG
CTCACATACGTACTTCTTAGTGGCGTGTCCCCCTTCCTGGATGACAGTGTGGAAGAGACC
TGCCTGAACATTTGCCGCTTAGACTTTAGCTTCCCAGATGACTACTTTAAAGGAGTGAGC
CAGAAGGCCAAGGAGTTCGTGTGCTTCCTCCTGCAGGAGGACCCCGCCAAGCGTCCCTCG
GCTGCGCTGGCCCTCCAGGAGCAGTGGCTGCAGGCCGGCAACGGCAGAAGCACGGGCGTC
CTCGACACGTCCAGACTGACTTCCTTCATTGAGCGGCGCAAACACCAGAATGATGTTCGA
CCTATCCGTAGCATTAAAAACTTTCTGCAGAGCAGGCTTCTGCCTAGAGTTTGA

• SH3_1 (PF00018 )
• Pkinase (PF00069 )
• I-set (PF07679 )
• RhoGEF (PF00621 )
• Spectrin (PF00435 )

• None

• None

>Triple functional domain protein
MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEM
KAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVC
KRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE
TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDI
LAKKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSG
NADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK
GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIR
QIASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDL
EDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDV
IHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSL
HRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFV
RRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTT
LQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKI
KLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNN
LTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHR
KHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKT
HQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTS
EQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRN
ADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQY
VVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLI
QLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQ
LDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLW
EMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKF
QMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELL
TCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTL
IRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVG
RTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRR
DGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRG
QTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVS
SNDASPPASVASLQPHMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKH
KKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEG
EEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSK
MALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVET
ERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLED
PEKLGSLFVKHERRLHMYIAYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKP
VQRIMKYQLLLKDFLKYSKKASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVA
QGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKV
SCLCLEENVENDPCKFALTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNAL
TSPIEYQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSR
IPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAE
GSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSP
LSSAVPSLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPG
KDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQI
LASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRK
KSEKKDKDGKREGKLENGYRKSREGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGE
TVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCI
AVNDMGSASSSASLRVLGPGMDGIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKR
AVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDC
VVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDA
VQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEET
CLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGRSTGV
LDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV

• 1NTY

1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S: Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004 Jan;36(1):40-5. Epub 2003 Dec 21. [PubMed:14702039 ]
2. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
3. Dephoure N, Zhou C, Villen J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP: A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10762-7. doi: 10.1073/pnas.0805139105. Epub 2008 Jul 31. [PubMed:18669648 ]
4. Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell. 2006 Nov 3;127(3):635-48. [PubMed:17081983 ]
5. Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal Chem. 2009 Jun 1;81(11):4493-501. doi: 10.1021/ac9004309. [PubMed:19413330 ]
6. Tao WA, Wollscheid B, O'Brien R, Eng JK, Li XJ, Bodenmiller B, Watts JD, Hood L, Aebersold R: Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. Nat Methods. 2005 Aug;2(8):591-8. [PubMed:16094384 ]
7. Schmutz J, Martin J, Terry A, Couronne O, Grimwood J, Lowry S, Gordon LA, Scott D, Xie G, Huang W, Hellsten U, Tran-Gyamfi M, She X, Prabhakar S, Aerts A, Altherr M, Bajorek E, Black S, Branscomb E, Caoile C, Challacombe JF, Chan YM, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Lopez F, Lou Y, Martinez D, Medina C, Morgan J, Nandkeshwar R, Noonan JP, Pitluck S, Pollard M, Predki P, Priest J, Ramirez L, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wheeler J, Wu K, Yang J, Dickson M, Cheng JF, Eichler EE, Olsen A, Pennacchio LA, Rokhsar DS, Richardson P, Lucas SM, Myers RM, Rubin EM: The DNA sequence and comparative analysis of human chromosome 5. Nature. 2004 Sep 16;431(7006):268-74. [PubMed:15372022 ]
8. Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR: Patterns of somatic mutation in human cancer genomes. Nature. 2007 Mar 8;446(7132):153-8. [PubMed:17344846 ]
9. Debant A, Serra-Pages C, Seipel K, O'Brien S, Tang M, Park SH, Streuli M: The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains. Proc Natl Acad Sci U S A. 1996 May 28;93(11):5466-71. [PubMed:8643598 ]
10. Seipel K, Medley QG, Kedersha NL, Zhang XA, O'Brien SP, Serra-Pages C, Hemler ME, Streuli M: Trio amino-terminal guanine nucleotide exchange factor domain expression promotes actin cytoskeleton reorganization, cell migration and anchorage-independent cell growth. J Cell Sci. 1999 Jun;112 ( Pt 12):1825-34. [PubMed:10341202 ]
11. Liu X, Wang H, Eberstadt M, Schnuchel A, Olejniczak ET, Meadows RP, Schkeryantz JM, Janowick DA, Harlan JE, Harris EA, Staunton DE, Fesik SW: NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio. Cell. 1998 Oct 16;95(2):269-77. [PubMed:9790533 ]