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Identification
HMDB Protein ID HMDBP08613
Secondary Accession Numbers
  • 14328
Name Triple functional domain protein
Synonyms
  1. PTPRF-interacting protein
Gene Name TRIO
Protein Type Unknown
Biological Properties
General Function Involved in Rho guanyl-nucleotide exchange factor activity
Specific Function Promotes the exchange of GDP by GTP. Together with leukocyte antigen-related (LAR) protein, it could play a role in coordinating cell-matrix and cytoskeletal rearrangements necessary for cell migration and cell growth
Pathways Not Available
Reactions Not Available
GO Classification
Component
cell part
intracellular
Function
small gtpase regulator activity
binding
ras guanyl-nucleotide exchange factor activity
catalytic activity
rho guanyl-nucleotide exchange factor activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
enzyme regulator activity
protein kinase activity
protein serine/threonine kinase activity
nucleoside-triphosphatase regulator activity
gtpase regulator activity
Process
phosphorus metabolic process
phosphate metabolic process
regulation of ras protein signal transduction
metabolic process
regulation of rho protein signal transduction
biological regulation
regulation of biological process
cellular metabolic process
regulation of cellular process
protein amino acid phosphorylation
regulation of cell communication
regulation of signal transduction
regulation of small gtpase mediated signal transduction
phosphorylation
Cellular Location
  1. Cytoplasm
Gene Properties
Chromosome Location Chromosome:5
Locus 5p15.2
SNPs TRIO
Gene Sequence
>9294 bp
ATGAGCGGCAGCAGCGGCGGAGCCGCCGCCCCCGCCGCGTCCTCCGGCCCCGCCGCGGCG
GCCAGCGCGGCTGGCTCGGGCTGCGGGGGCGGTGCCGGCGAGGGGGCAGAGGAGGCGGCC
AAGGACCTGGCCGACATCGCGGCCTTCTTCCGATCCGGGTTTCGAAAAAACGATGAAATG
AAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGA
GATAAACGTGGAGGTCCCATTTTAACGTTTCCGGCCCGCAGCAATCATGACAGAATACGA
CAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCCTGTATTCCCAGCGAGGAGGTCTGC
AAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCC
CTTCTGAAGATCCTGCAGGAGTCCTTCCCCTGCTGCATCCATGTGGCCCTGATCATCAAG
CCAGACAACTTCTGGCAGAAACAGAGGACTAATTTTGGCAGTTCTAAATTTGAATTTGAG
ACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCT
GAGTTTGATGGCTGCCTGGAATACAACCACGAAGAATGGATTGAAATCAGAGTTGCTTTT
GAAGACTACATTAGCAATGCCACCCACATGCTGTCTCGGCTGGAGGAACTTCAGGACATC
CTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACAT
TCTCAGCTGAAGAAGAAGGTGATTAAGGCCCCCATCGAGGACCTGGATTTGGAGGGACAG
AAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTTCCCAAAAAGAACTCAGGCTCAGGC
AATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCG
ACACGGCAGCATCTGCACCAGATGTGGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTC
CAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATGTTTGACTGGATCACACACAACAAA
GGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTT
CAGACGCAGCACAATCACTTTGCCATGAACTGTATGAACGTGTATGTAAATATAAACCGC
ATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGCCACTATGCCTCGCAGCAGATCAGG
CAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGG
AGCACCTTGCTGGACATGTCCTCCATTTTCCACCAGAAGGCCGAAAAGTATATGAGCAAC
GTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGACCTTCCCTCAGAGCTGCAGGACCTA
GAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAG
GTCAGCCAAGATGGGAAGTCGCTCCTTGACAAGCTCCAGCGGCCCTTGACTCCCGGCAGC
TCCGATTCCCTGACAGCCTCTGCCAACTACTCCAAGGCCGTGCACCATGTCCTGGATGTC
ATCCACGAGGTGCTGCACCACCAGCGGCAGCTGGAGAACATCTGGCAACACCGCAAGGTC
CGGCTGCATCAGAGGCTGCAGCTGTGTGTTTTCCAGCAGGACGTTCAGCAGGTGCTAGAC
TGGATCGAGAACCACGGAGAAGCATTTCTGAGCAAACATACAGGTGTGGGGAAATCTCTT
CATCGGGCCAGAGCATTGCAGAAACGTCATGAAGATTTTGAAGAAGTGGCACAGAACACA
TACACCAATGCGGATAAATTACTGGAAGCAGCAGAACAGCTGGCTCAGACTGGGGAATGT
GACCCCGAAGAGATTTATCAGGCTGCCCATCAGCTGGAAGACCGGATTCAAGATTTCGTT
CGGCGTGTTGAGCAGCGAAAGATCCTACTGGACATGTCAGTGTCCTTTCACACCCATGTG
AAAGAGCTGTGGACGTGGCTGGAGGAGCTGCAGAAGGAGCTGCTGGACGACGTGTATGCC
GAGTCGGTGGAGGCCGTGCAGGACCTCATCAAGCGCTTTGGCCAGCAGCAGCAGACCACC
CTGCAGGTGACTGTCAACGTGATCAAGGAAGGGGAGGACCTCATCCAGCAGCTCAGGGAC
TCTGCCATCTCCAGTAACAAGACCCCCCACAACAGCTCCATCAACCACATTGAGACGGTG
CTGCAGCAGCTGGACGAGGCGCAGTCGCAGATGGAGGAGCTCTTCCAGGAGCGCAAGATC
AAGCTGGAGCTCTTCCTGCAGCTGCGCATCTTCGAGAGGGACGCCATCGACATTATCTCA
GACCTCGAGTCTTGGAATGATGAGCTTTCTCAGCAAATGAATGACTTCGACACAGAAGAT
CTCACGATTGCAGAGCAGCGCCTCCAGCACCATGCAGACAAAGCCTTGACCATGAACAAC
TTGACTTTTGACGTCATCCACCAAGGGCAAGATCTTCTGCAGTATGTCAATGAGGTCCAG
GCCTCTGGTGTGGAGCTGCTGTGTGATAGAGATGTAGACATGGCAACTCGGGTCCAGGAC
CTGCTGGAGTTTCTTCATGAAAAACAGCAGGAATTGGATTTAGCCGCAGAGCAGCATCGG
AAACACCTGGAGCAGTGCGTGCAGCTGCGCCACCTGCAGGCAGAAGTGAAACAGGTGCTG
GGTTGGATCCGCAACGGAGAGTCCATGTTAAATGCCGGACTTATCACAGCCAGCTCGTTA
CAAGAGGCAGAGCAGCTCCAGCGAGAGCACGAGCAGTTCCAGCATGCCATTGAGAAAACA
CATCAGAGCGCGCTGCAGGTGCAGCAGAAGGCAGAAGCCATGCTACAGGCCAACCACTAC
GACATGGACATGATCCGGGACTGCGCCGAGAAGGTGGCGTCTCACTGGCAACAGCTCATG
CTCAAGATGGAAGATCGCCTCAAGCTCGTCAACGCCTCTGTCGCTTTCTACAAAACCTCA
GAGCAGGTCTGCAGCGTCCTCGAGAGCCTGGAACAGGAGTACAAGAGAGAAGAAGACTGG
TGTGGCGGGGCGGATAAGCTGGGCCCAAACTCTGAGACGGACCACGTGACGCCCATGATC
AGCAAGCACCTGGAGCAGAAGGAGGCATTCCTGAAGGCTTGCACCCTTGCTCGGAGGAAT
GCAGACGTCTTCCTGAAATACCTGCACAGGAACAGCGTGAACATGCCAGGAATGGTGACG
CACATCAAAGCTCCTGAACAGCAAGTGAAAAATATCTTGAATGAACTCTTCCAACGGGAG
AACAGGGTATTGCATTACTGGACCATGAGGAAGAGACGGCTGGACCAGTGTCAGCAGTAC
GTGGTCTTTGAGAGGAGTGCCAAGCAGGCTTTGGAATGGATCCATGACAATGGCGAGTTC
TACCTTTCCACACACACCTCCACGGGCTCCAGTATACAGCACACCCAGGAGCTCCTGAAA
GAGCACGAGGAGTTCCAGATAACTGCAAAGCAAACCAAAGAGAGAGTGAAGCTATTGATA
CAGCTGGCTGATGGCTTTTGTGAAAAAGGGCATGCCCATGCGGCAGAGATAAAAAAATGT
GTTACTGCTGTGGATAAGAGGTACAGAGATTTCTCTCTGCGGATGGAGAAGTACAGGACC
TCTTTGGAAAAAGCCCTGGGGATTTCTTCAGATTCCAACAAATCGAGTAAAAGTCTCCAG
CTAGATATCATTCCAGCCAGTATCCCTGGCTCAGAGGTGAAACTTCGAGATGCTGCTCAT
GAACTTAATGAAGAGAAGCGGAAATCTGCCCGCAGGAAAGAGTTCATAATGGCTGAGCTC
ATTCAAACTGAAAAGGCTTATGTAAGAGACCTCCGGGAATGTATGGATACGTACCTGTGG
GAAATGACCAGTGGCGTGGAAGAGATTCCACCTGGCATTGTAAACAAAGAACTCATCATC
TTCGGAAACATGCAAGAAATCTACGAATTTCATAATAACATATTCCTAAAGGAGCTGGAA
AAATATGAACAGTTGCCAGAGGATGTTGGACATTGTTTTGTTACTTGGGCAGACAAGTTT
CAGATGTATGTCACATATTGCAAAAATAAGCCTGATTCTACTCAGCTGATATTGGAACAT
GCAGGGTCCTATTTTGACGAGATACAGCAGCGACATGGATTAGCCAATTCCATTTCTTCC
TACCTTATTAAACCAGTTCAGCGAATAACGAAGTATCAGCTCCTTTTAAAAGAGCTGCTG
ACGTGCTGTGAGGAAGGAAAGGGAGAGATTAAAGATGGCCTGGAGGTGATGCTCAGCGTG
CCGAAGCGAGCCAATGATGCCATGCACCTCAGCATGCTGGAAGGGTTTGATGAAAACATT
GAGTCTCAGGGAGAACTCATCCTACAGGAATCCTTCCAAGTGTGGGACCCAAAAACCTTA
ATTCGAAAGGGTCGAGAACGGCATCTCTTCCTTTTTGAAATGTCCTTAGTATTTAGTAAA
GAAGTGAAAGATTCCAGTGGGAGAAGCAAGTACCTTTATAAAAGCAAATTGTTTACCTCA
GAGTTGGGTGTCACAGAACATGTTGAAGGAGACCCTTGCAAATTTGCACTGTGGGTGGGG
AGAACACCAACTTCAGATAATAAAATTGTCCTTAAGGCTTCCAGCATAGAGAACAAGCAG
GACTGGATAAAGCATATCCGCGAAGTCATCCAGGAGCGGACGATCCACCTGAAGGGAGCC
CTGAAGGAGCCCATTCACATCCCTAAGACCGCTCCCGCCACAAGACAGAAGGGAAGGAGG
GATGGAGAGGATCTGGACAGCCAAGGAGACGGCAGCAGCCAGCCTGATACGATTTCCATC
GCCTCACGGACGTCTCAGAACACGCTGGACAGCGATAAGCTCTCTGGTGGCTGTGAGCTG
ACAGTGGTGATCCATGACTTCACCGCTTGCAACAGCAACGAGCTGACCATCCGACGGGGC
CAGACCGTGGAAGTTCTGGAGCGGCCGCATGACAAGCCTGACTGGTGTCTGGTGCGGACA
ACTGACCGCTCCCCAGCGGCAGAAGGCCTGGTCCCCTGTGGTTCACTGTGCATCGCCCAC
TCCAGAAGTAGCATGGAAATGGAGGGCATCTTCAACCACAAAGACTCGCTCTCCGTCTCC
AGCAATGACGCCAGTCCACCCGCATCCGTGGCTTCCCTCCAGCCCCACATGATCGGGGCC
CAGAGCTCGCCGGGCCCCAAGCGGCCGGGCAACACCCTGCGCAAGTGGCTCACCAGCCCC
GTGCGGCGGCTCAGCAGCGGCAAGGCCGACGGGCACGTGAAGAAGCTGGCGCACAAGCAC
AAGAAGAGCCGCGAGGTCCGCAAGAGCGCCGACGCCGGCTCGCAGAAGGACTCCGACGAC
AGTGCGGCCACCCCGCAGGACGAGACGGTCGAGGAGAGAGGCCGGAACGAGGGCCTGAGC
AGCGGTACTCTCTCCAAATCCTCCTCCTCGGGGATGCAGAGCTGTGGAGAAGAGGAAGGC
GAGGAGGGGGCCGACGCCGTGCCCCTGCCGCCACCCATGGCCATCCAGCAGCACAGCCTC
CTCCAGCCAGACTCACAGGATGACAAGGCCTCTTCTCGGTTATTAGTCCGCCCCACCAGC
TCCGAAACACCGAGTGCAGCCGAGCTCGTCAGTGCAATTGAGGAACTCGTGAAAAGCAAG
ATGGCACTGGAGGATCGCCCCAGCTCACTCCTTGTTGACCAGGGAGATAGTAGCAGCCCT
TCCTTCAACCCTTCGGATAATTCCCTTCTCTCTTCCTCCTCGCCCATTGATGAGATGGAA
GAAAGGAAATCCAGCTCTTTAAAGAGAAGACACTACGTTTTGCAAGAACTAGTGGAGACA
GAGCGTGACTATGTGCGGGACCTTGGCTATGTGGTTGAGGGCTACATGGCACTTATGAAA
GAAGATGGTGTTCCTGATGACATGAAAGGAAAAGACAAAATTGTGTTCGGCAACATCCAT
CAGATTTACGACTGGCACAGAGACTTTTTTTTAGGAGAGTTAGAGAAGTGCCTTGAAGAT
CCAGAAAAACTAGGATCCCTTTTTGTTAAACACGAGAGAAGGTTGCACATGTACATAGCT
TATTGTCAAAATAAACCAAAGTCTGAGCACATTGTCTCAGAATACATTGATACCTTTTTT
GAGGACTTAAAGCAGCGTCTTGGCCACAGGTTACAGCTCACAGATCTGTTGATCAAACCA
GTGCAGAGAATCATGAAGTATCAGCTGTTACTGAAGGACTTCCTCAAGTATTCCAAAAAG
GCCAGCCTGGATACATCAGAATTAGAGAGAGCTGTGGAAGTCATGTGCATAGTACCCAGG
CGGTGCAACGACATGATGAACGTGGGGCGGCTGCAAGGATTCGACGGGAAAATCGTTGCC
CAGGGTAAACTGCTCTTGCAGGACACATTCTTGGTCACAGACCAAGATGCAGGACTTCTG
CCTCGCTGCAGAGAGAGGCGCATCTTCCTCTTTGAGCAGATCGTCATATTCAGCGAACCA
CTTGATAAAAAGAAGGGCTTCTCCATGCCGGGATTCCTGTTTAAGAACAGTATCAAGGTG
AGTTGCCTTTGCCTGGAGGAAAATGTGGAAAATGATCCCTGTAAATTTGCTCTGACATCG
AGGACGGGTGACGTGGTAGAGACCTTCATTTTGCATTCATCTAGTCCAAGTGTCCGGCAA
ACTTGGATCCATGAAATCAACCAAATTTTAGAAAACCAGCGCAATTTTTTAAATGCCTTG
ACATCGCCAATCGAGTACCAGAGGAACCACAGCGGGGGCGGCGGCGGCGGCGGCAGCGGG
GGCAGCGGCGGGGGTGGGGGCAGCGGCGGCGGCGGGGCCCCCAGTGGCGGCAGCGGCCAC
AGTGGCGGCCCCAGCAGCTGCGGCGGCGCCCCCAGCACGAGCAGGAGCCGGCCCTCCCGG
ATCCCCCAGCCTGTCCGACACCACCCCCCCGTGCTGGTCTCCTCTGCAGCCTCGAGCCAG
GCAGAGGCAGACAAGATGTCAGGTACGTCCACCCCCGGGCCCTCCCTGCCTCCCCCTGGC
GCGGCCCCCGAGGCCGGCCCCAGCGCGCCCAGCAGGCGGCCCCCCGGCGCGGACGCCGAG
GGGTCCGAGCGAGAAGCGGAGCCGATCCCCAAGATGAAGGTGCTGGAGAGCCCCAGGAAA
GGCGCCGCGAACGCCTCGGGGTCGAGCCCAGACGCCCCCGCCAAGGACGCGCGCGCTAGC
CTGGGCACCCTGCCGCTTGGGAAGCCCCGGGCCGGGGCCGCTTCGCCGCTGAACTCGCCG
CTCTCCAGCGCGGTCCCTTCTCTCGGCAAGGAGCCCTTCCCCCCCAGCAGCCCCCTGCAG
AAGGGGGGCTCCTTCTGGAGCTCCATCCCCGCCTCCCCCGCCAGCCGACCCGGCTCCTTC
ACCTTCCCGGGGGACAGCGACTCCCTCCAGCGGCAGACACCCCGCCACGCGGCCCCTGGC
AAGGATACTGACCGCATGAGCACGTGCTCCTCGGCCAGCGAGCAGTCCGTGCAGTCCACC
CAGAGCAACGGGAGTGAAAGCAGCAGCAGTAGCAACATCTCCACCATGTTGGTGACACAC
GATTACACGGCAGTGAAGGAGGATGAGATCAACGTCTACCAAGGAGAGGTCGTTCAAATT
CTGGCCAGCAACCAGCAGAACATGTTTCTGGTGTTCCGAGCCGCCACTGACCAGTGCCCC
GCAGCTGAGGGCTGGATTCCAGGCTTTGTCCTGGGCCACACCAGTGCAGTCATCGTGGAG
AACCCGGACGGGACTCTCAAGAAGTCAACATCTTGGCACACAGCACTCCGTTTAAGGAAA
AAATCTGAGAAAAAAGATAAAGACGGCAAAAGGGAAGGCAAGTTAGAGAACGGTTATCGG
AAGTCACGGGAAGGACTCAGCAACAAGGTATCTGTGAAGCTTCTCAATCCCAACTACATT
TATGACGTTCCCCCAGAATTCGTCATTCCATTGAGTGAGGTCACGTGTGAGACAGGGGAG
ACCGTTGTTCTTAGATGTCGAGTCTGTGGCCGCCCCAAAGCCTCAATTACCTGGAAGGGC
CCTGAACACAACACCTTGAACAACGATGGTCACTACAGCATCTCCTACAGTGACCTGGGA
GAGGCCACGCTGAAGATTGTGGGCGTGACCACGGAAGATGACGGCATCTACACGTGCATC
GCTGTCAATGACATGGGTTCAGCCTCATCGTCGGCCAGCCTGAGGGTCCTAGGTCCAGGG
ATGGATGGGATCATGGTGACCTGGAAAGACAACTTTGACTCCTTCTACAGTGAAGTGGCT
GAGCTTGGCAGGGGCAGATTCTCTGTCGTTAAGAAATGTGATCAGAAAGGAACCAAGCGA
GCAGTGGCCACTAAGTTTGTGAACAAGAAGTTGATGAAGCGCGACCAGGTCACCCATGAG
CTTGGCATCCTGCAGAGCCTCCAGCACCCCCTGCTTGTCGGCCTCCTCGACACCTTTGAG
ACCCCCACCAGCTACATCCTGGTCTTAGAAATGGCTGACCAGGGTCGCCTCCTGGACTGC
GTGGTGCGATGGGGAAGCCTCACTGAAGGGAAGATCAGGGCGCACCTGGGGGAGGTTCTG
GAAGCTGTCCGGTACCTGCACAACTGCAGGATAGCACACCTGGACCTAAAGCCTGAGAAT
ATCCTGGTGGATGAGAGTTTAGCCAAGCCAACCATCAAACTGGCTGACTTTGGAGATGCT
GTTCAGCTCAACACGACCTACTACATCCACCAGTTACTGGGGAACCCTGAATTCGCAGCC
CCTGAAATCATCCTCGGGAACCCTGTCTCCCTGACCTCGGATACGTGGAGTGTTGGAGTG
CTCACATACGTACTTCTTAGTGGCGTGTCCCCCTTCCTGGATGACAGTGTGGAAGAGACC
TGCCTGAACATTTGCCGCTTAGACTTTAGCTTCCCAGATGACTACTTTAAAGGAGTGAGC
CAGAAGGCCAAGGAGTTCGTGTGCTTCCTCCTGCAGGAGGACCCCGCCAAGCGTCCCTCG
GCTGCGCTGGCCCTCCAGGAGCAGTGGCTGCAGGCCGGCAACGGCAGAAGCACGGGCGTC
CTCGACACGTCCAGACTGACTTCCTTCATTGAGCGGCGCAAACACCAGAATGATGTTCGA
CCTATCCGTAGCATTAAAAACTTTCTGCAGAGCAGGCTTCTGCCTAGAGTTTGA
Protein Properties
Number of Residues 3097
Molecular Weight 346897.2
Theoretical pI 6.32
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Triple functional domain protein
MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEM
KAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVC
KRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE
TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDI
LAKKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSG
NADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK
GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIR
QIASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDL
EDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDV
IHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSL
HRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFV
RRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTT
LQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKI
KLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNN
LTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHR
KHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKT
HQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTS
EQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRN
ADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQY
VVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLI
QLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQ
LDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLW
EMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKF
QMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELL
TCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTL
IRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVG
RTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRR
DGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRG
QTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVS
SNDASPPASVASLQPHMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKH
KKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEG
EEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSK
MALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVET
ERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLED
PEKLGSLFVKHERRLHMYIAYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKP
VQRIMKYQLLLKDFLKYSKKASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVA
QGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKV
SCLCLEENVENDPCKFALTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNAL
TSPIEYQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSR
IPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAE
GSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSP
LSSAVPSLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPG
KDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQI
LASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRK
KSEKKDKDGKREGKLENGYRKSREGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGE
TVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCI
AVNDMGSASSSASLRVLGPGMDGIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKR
AVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDC
VVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDA
VQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEET
CLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGRSTGV
LDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV
GenBank ID Protein 45439359
UniProtKB/Swiss-Prot ID O75962
UniProtKB/Swiss-Prot Entry Name TRIO_HUMAN
PDB IDs
GenBank Gene ID NM_007118.2
GeneCard ID TRIO
GenAtlas ID TRIO
HGNC ID HGNC:12303
References
General References
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