Hmdb loader
Identification
HMDB Protein ID HMDBP08639
Secondary Accession Numbers
  • 14355
Name Cytochrome P450 2W1
Synonyms
  1. CYPIIW1
Gene Name CYP2W1
Protein Type Unknown
Biological Properties
General Function Involved in monooxygenase activity
Specific Function Not Available
Pathways Not Available
Reactions Not Available
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
catalytic activity
transition metal ion binding
electron carrier activity
iron ion binding
monooxygenase activity
heme binding
oxidoreductase activity
Process
metabolic process
oxidation reduction
Cellular Location
  1. Membrane
  2. Endoplasmic reticulum membrane (Potential)
  3. Peripheral membrane protein (Potential)
Gene Properties
Chromosome Location Chromosome:7
Locus 7p22.3
SNPs CYP2W1
Gene Sequence
>1473 bp
ATGGCCCTGCTGCTCTTGCTGTTCCTGGGCCTCCTGGGGCTCTGGGGGCTGCTCTGCGCC
TGCGCCCAAGACCCCTCCCCAGCTGCCCGGTGGCCCCCGGGGCCTCGCCCGCTGCCGCTC
GTCGGGAACCTGCACTTGCTGCGTCTGTCGCAACAGGACCGGTCCCTGATGGAGCTCTCA
GAACGCTACGGGCCGGTGTTCACCGTGCACCTGGGGCGCCAGAAGACGGTGGTGCTGACG
GGGTTCGAGGCGGTCAAAGAGGCGCTGGCGGGCCCCGGGCAGGAGCTGGCCGACCGGCCT
CCCATCGCCATCTTCCAGCTCATCCAGCGAGGTGGAGGCATCTTCTTCTCATCTGGGGCG
CGCTGGAGGGCTGCCCGCCAGTTCACGGTGCGTGCCCTGCACAGCCTGGGCGTGGGCCGG
GAGCCGGTGGCTGACAAGATTCTGCAGGAGCTGAAATGCCTCTCTGGGCAGCTGGATGGC
TACAGAGGCCGGCCCTTCCCGCTGGCCCTACTGGGCTGGGCTCCCTCCAATATCACCTTC
GCGCTCCTCTTCGGCCGCCGATTTGACTACCGGGACCCCGTGTTTGTGTCCCTGCTGGGT
CTCATCGATGAGGTCATGGTCCTCTTGGGGTCCCCTGGCCTGCAGCTGTTCAACGTCTAC
CCATGGCTCGGGGCCCTGCTCCAGCTGCACCGGCCCGTCCTGCGCAAGATCGAGGAGGTC
CGTGCCATTCTGAGGACCCTCCTGGAGGCGCGGAGGCCCCACGTGTGCCCGGGGGACCCC
GTGTGCAGCTATGTGGACGCCCTGATCCAGCAGGGACAGGGGGATGACCCCGAGGGCCTG
TTTGCTGAGGCCAACGCGGTGGCCTGCACCCTGGACATGGTCATGGCCGGGACGGAGACG
ACCTCGGCCACGCTGCAGTGGGCCGCACTTCTGATGGGCCGGCACCCGGACGTGCAGGGC
CGGGTGCAGGAGGAGCTAGACCGCGTGCTGGGCCCTGGGCGGACTCCCCGGCTGGAGGAC
CAGCAGGCTCTGCCCTACACAAGCGCCGTGCTCCACGAGGTGCAGCGGTTCATCACGCTC
CTGCCGCACGTGCCCCGCTGCACCGCGGCCGACACACAGCTGGGCGGCTTCCTGCTCCCC
AAGGGCACGCCCGTGATTCCCCTGCTGACCTCGGTGCTCCTGGATGAGACACAGTGGCAG
ACCCCAGGCCAGTTCAACCCCGGCCATTTCCTGGACGCGAATGGGCACTTTGTGAAGCGG
GAGGCCTTCCTGCCTTTCTCTGCAGGCCGCCGCGTCTGTGTTGGGGAGCGCCTGGCCAGG
ACCGAGCTCTTCCTGCTGTTTGCCGGCCTCCTGCAGAGGTACCGCCTGCTGCCCCCGCCT
GGCGTCAGTCCGGCCTCCCTGGACACCACGCCCGCCCGGGCTTTTACCATGAGGCCGAGG
GCCCAGGCCCTGTGTGCGGTGCCCAGGCCCTAG
Protein Properties
Number of Residues 490
Molecular Weight 53843.2
Theoretical pI 8.81
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Cytochrome P450 2W1
MALLLLLFLGLLGLWGLLCACAQDPSPAARWPPGPRPLPLVGNLHLLRLSQQDRSLMELS
ERYGPVFTVHLGRQKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRGGGIFFSSGA
RWRAARQFTVRALHSLGVGREPVADKILQELKCLSGQLDGYRGRPFPLALLGWAPSNITF
ALLFGRRFDYRDPVFVSLLGLIDEVMVLLGSPGLQLFNVYPWLGALLQLHRPVLRKIEEV
RAILRTLLEARRPHVCPGDPVCSYVDALIQQGQGDDPEGLFAEANAVACTLDMVMAGTET
TSATLQWAALLMGRHPDVQGRVQEELDRVLGPGRTPRLEDQQALPYTSAVLHEVQRFITL
LPHVPRCTAADTQLGGFLLPKGTPVIPLLTSVLLDETQWQTPGQFNPGHFLDANGHFVKR
EAFLPFSAGRRVCVGERLARTELFLLFAGLLQRYRLLPPPGVSPASLDTTPARAFTMRPR
AQALCAVPRP
GenBank ID Protein 68086539
UniProtKB/Swiss-Prot ID Q8TAV3
UniProtKB/Swiss-Prot Entry Name CP2W1_HUMAN
PDB IDs Not Available
GenBank Gene ID BC025761
GeneCard ID CYP2W1
GenAtlas ID CYP2W1
HGNC ID HGNC:20243
References
General References
  1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]