Showing Protein Beta,beta-carotene 9',10'-oxygenase (HMDBP08670)

• 14389

1. B-diox-II
2. Beta-carotene dioxygenase 2

>1740 bp
ATGTTTTTTCGAGTCTTTCTCCATTTTATCAGGAGTCATTCTGCCACTGCAGTGGATTTC
CTTCCTGTGATGGTGCACCGGCTCCCAGTTTTCAAAAGGTACATGGGAAATACTCCTCAG
AAAAAAGCCGTCTTTGGGCAGTGTCGGGGTCTGCCATGTGTTGCACCGCTGCTGACCACA
GTGGAAGAGGCTCCACGGGGCATCTCTGCTCGAGTCTGGGGACATTTTCCTAAGTGGCTC
AATGGCTCTCTACTTCGAATTGGACCTGGGAAATTCGAGTTTGGGAAGGATAAGTACAAT
CATTGGTTTGATGGGATGGCGCTGCTTCACCAGTTCAGAATGGCAAAGGGCACAGTGACA
TACAGGAGCAAGTTTCTACAGAGTGATACATATAAGGCCAACAGTGCTAAAAACCGAATT
GTGATCTCAGAATTTGGCACACTGGCTCTCCCGGATCCATGCAAGAATGTTTTTGAACGT
TTCATGTCCAGGTTTGAGCTGCCTGGTAAAGCTGCAGCCATGACTGACAATACTAATGTC
AACTATGTGCGGTACAAGGGTGATTACTACCTCTGCACTGAGACCAACTTTATGAATAAA
GTGGACATTGAAACTCTGGAAAAAACAGAAAAGGTAGATTGGAGCAAATTTATTGCTGTG
AATGGAGCAACTGCACATCCTCATTATGACCTGGATGGAACAGCATACAATATGGGGAAC
TCCTTTGGGCCATATGGTTTCTCCTATAAGGTTATTCGGGTTCCTCCAGAGAAGGTGGAC
CTTGGGGAGACAATCCATGGAGTCCAGGTGATATGTTCTATTGCTTCTACAGAGAAAGGG
AAACCTTCTTACTACCATAGCTTTGGAATGACAAGGAACTATATAATTTTCATTGAACAA
CCTCTAAAGATGAACCTGTGGAAAATTGCCACTTCTAAAATTCGGGGAAAGGCCTTTTCA
GATGGGATAAGCTGGGAACCCCAGTGTAATACGCGGTTTCATGTGGTGGAAAAACGCACT
GGACAGCTCCTTCCAGGGAGATACTACAGCAAACCTTTTGTTACATTTCATCAAATCAAT
GCCTTTGAGGACCAGGGCTGTGTTATAATTGATTTGTGCTGTCAAGATAATGGAAGAACC
CTAGAAGTTTACCAGTTACAGAATCTCAGGAAGGCTGGGGAAGGGCTTGATCAGGTCCAT
AATTCAGCAGCCAAATCTTTCCCTCGAAGGTTTGTTTTGCCTTTAAATGTCAGTTTGAAT
GCCCCTGAGGGAGACAACCTGAGTCCATTGTCCTATACTTCAGCCAGTGCTGTGAAACAG
GCTGATGGAACGATCTGGTGCTCTCATGAAAATCTACATCAGGAGGACCTAGAAAAGGAA
GGAGGCATTGAATTTCCTCAGATCTACTATGATCGATTCAGTGGCAAAAAGTATCATTTC
TTTTATGGCTGTGGCTTTCGGCATTTAGTGGGGGATTCTCTGATCAAGGTTGATGTGGTG
AATAAGACACTGAAGGTTTGGAGAGAAGATGGCTTTTATCCCTCAGAACCTGTTTTTGTT
CCAGCACCAGGAACCAATGAAGAAGATGGTGGGGTTATTCTTTCTGTGGTGATCACTCCC
AACCAGAATGAAAGCAATTTTATCCTAGTTTTGGATGCCAAGAACTTTGAAGAGCTGGGC
CGAGCAGAGGTACCTGTGCAGATGCCTTATGGGTTCCATGGTACCTTCATACCCATCTGA

• RPE65 (PF03055 )

>Beta,beta-carotene 9',10'-oxygenase
MFFRVFLHFIRSHSATAVDFLPVMVHRLPVFKRYMGNTPQKKAVFGQCRGLPCVAPLLTT
VEEAPRGISARVWGHFPKWLNGSLLRIGPGKFEFGKDKYNHWFDGMALLHQFRMAKGTVT
YRSKFLQSDTYKANSAKNRIVISEFGTLALPDPCKNVFERFMSRFELPGKAAAMTDNTNV
NYVRYKGDYYLCTETNFMNKVDIETLEKTEKVDWSKFIAVNGATAHPHYDLDGTAYNMGN
SFGPYGFSYKVIRVPPEKVDLGETIHGVQVICSIASTEKGKPSYYHSFGMTRNYIIFIEQ
PLKMNLWKIATSKIRGKAFSDGISWEPQCNTRFHVVEKRTGQLLPGRYYSKPFVTFHQIN
AFEDQGCVIIDLCCQDNGRTLEVYQLQNLRKAGEGLDQVHNSAAKSFPRRFVLPLNVSLN
APEGDNLSPLSYTSASAVKQADGTIWCSHENLHQEDLEKEGGIEFPQIYYDRFSGKKYHF
FYGCGFRHLVGDSLIKVDVVNKTLKVWREDGFYPSEPVFVPAPGTNEEDGGVILSVVITP
NQNESNFILVLDAKNFEELGRAEVPVQMPYGFHGTFIPI

1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S: Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004 Jan;36(1):40-5. Epub 2003 Dec 21. [PubMed:14702039 ]
2. Taylor TD, Noguchi H, Totoki Y, Toyoda A, Kuroki Y, Dewar K, Lloyd C, Itoh T, Takeda T, Kim DW, She X, Barlow KF, Bloom T, Bruford E, Chang JL, Cuomo CA, Eichler E, FitzGerald MG, Jaffe DB, LaButti K, Nicol R, Park HS, Seaman C, Sougnez C, Yang X, Zimmer AR, Zody MC, Birren BW, Nusbaum C, Fujiyama A, Hattori M, Rogers J, Lander ES, Sakaki Y: Human chromosome 11 DNA sequence and analysis including novel gene identification. Nature. 2006 Mar 23;440(7083):497-500. [PubMed:16554811 ]
3. Kiefer C, Hessel S, Lampert JM, Vogt K, Lederer MO, Breithaupt DE, von Lintig J: Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A. J Biol Chem. 2001 Apr 27;276(17):14110-6. Epub 2001 Jan 29. [PubMed:11278918 ]
4. Lindqvist A, He YG, Andersson S: Cell type-specific expression of beta-carotene 9',10'-monooxygenase in human tissues. J Histochem Cytochem. 2005 Nov;53(11):1403-12. Epub 2005 Jun 27. [PubMed:15983114 ]