Hmdb loader
Identification
HMDB Protein ID HMDBP08802
Secondary Accession Numbers
  • 14526
Name L-seryl-tRNA(Sec) kinase
Synonyms
  1. O-phosphoseryl-tRNA(Sec) kinase
Gene Name PSTK
Protein Type Unknown
Biological Properties
General Function Involved in ATP binding
Specific Function Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:1
Locus 10q26.13
SNPs PSTK
Gene Sequence
>1047 bp
ATGAAGACCGCCGAGAACATCAGAGGAACCGGCAGCGACGGGCCGCGGAAACGAGGCCTC
TGCGTCCTCTGTGGCCTCCCCGCGGCAGGAAAATCGACTTTCGCGCGCGCCCTCGCCCAC
CGGCTGCAGCAGGAGCAGGGTTGGGCCATCGGTGTTGTCGCGTATGATGACGTCATGCCC
GACGCGTTTCTCGCCGGGGCAAGAGCGCGACCGGCGCCATCCCAATGGAAATTGCTTCGA
CAGGAACTGTTGAAGTACCTGGAATACTTCTTGATGGCTGTCATTAATGGGTGTCAGATG
TCTGTCCCACCCAACAGGACTGAAGCCATGTGGGAAGATTTTATAACCTGCTTAAAGGAT
CAAGATCTGATATTTTCTGCAGCATTTGAGGCCCAGTCTTGCTACCTCTTAACAAAAACT
GCTGTTTCTAGACCTTTGTTTTTGGTTTTGGATGACAATTTTTATTATCAGAGTATGAGA
TATGAAGTCTACCAGCTGGCTCGGAAATATTCGTTGGGCTTTTGCCAGCTCTTTTTAGAT
TGTCCTCTTGAGACCTGTTTACAGAGGAATGGCCAGAGGCCACAGGCACTGCCTCCTGAG
ACCATCCACCTGATGGGAAGAAAGCTAGAAAAGCCCAACCCTGAGAAAAATGCTTGGGAA
CACAACAGCCTCACAATTCCGAGTCCAGCATGTGCTTCGGAGGCCAGCCTGGAAGTGACT
GATTTATTGCTCACTGCTTTGGAAAATCCAGTAAAATATGCTGAGGACAATATGGAACAA
AAGGACACAGACAGAATTATTTGTTCAACTAACATTCTTCATAAAACTGATCAGACACTC
CGAAGGATTGTATCTCAGACAATGAAGGAAGCAAAAGGTAATCAGGAAGCCTTCTCAGAG
ATGACATTTAAGCAAAGATGGGTAAGAGCGAACCATGCAGCTATCTGGAGGATCATTCTA
GGCAATGAACACATCAAGTGCAGAAGCGCAAAGGTTGGCTGGTTGCAGTGTTGCAGAATC
GAGAAGAGGCCATTGAGCACGGGGTGA
Protein Properties
Number of Residues 348
Molecular Weight 39526.2
Theoretical pI 8.36
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>L-seryl-tRNA(Sec) kinase
MKTAENIRGTGSDGPRKRGLCVLCGLPAAGKSTFARALAHRLQQEQGWAIGVVAYDDVMP
DAFLAGARARPAPSQWKLLRQELLKYLEYFLMAVINGCQMSVPPNRTEAMWEDFITCLKD
QDLIFSAAFEAQSCYLLTKTAVSRPLFLVLDDNFYYQSMRYEVYQLARKYSLGFCQLFLD
CPLETCLQRNGQRPQALPPETIHLMGRKLEKPNPEKNAWEHNSLTIPSPACASEASLEVT
DLLLTALENPVKYAEDNMEQKDTDRIICSTNILHKTDQTLRRIVSQTMKEAKGNQEAFSE
MTFKQRWVRANHAAIWRIILGNEHIKCRSAKVGWLQCCRIEKRPLSTG
GenBank ID Protein 224465209
UniProtKB/Swiss-Prot ID Q8IV42
UniProtKB/Swiss-Prot Entry Name PSTK_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_153336.2
GeneCard ID PSTK
GenAtlas ID PSTK
HGNC ID HGNC:28578
References
General References
  1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S: Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004 Jan;36(1):40-5. Epub 2003 Dec 21. [PubMed:14702039 ]
  2. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]