Showing Protein Interferon-stimulated gene 20 kDa protein (HMDBP08843)

• 14570

1. Estrogen-regulated transcript 45 protein
2. Promyelocytic leukemia nuclear body-associated protein ISG20

1. Nucleus

>546 bp
ATGGCTGGGAGCCGTGAGGTGGTGGCCATGGACTGCGAGATGGTGGGGCTGGGGCCCCAC
CGGGAGAGTGGCCTGGCTCGTTGCAGCCTCGTGAACGTCCACGGTGCTGTGCTGTACGAC
AAGTTCATCCGGCCTGAGGGAGAGATCACCGATTACAGAACCCGGGTCAGCGGGGTCACC
CCTCAGCACATGGTGGGGGCCACACCATTTGCCGTGGCCAGGCTAGAGATCCTGCAGCTC
CTGAAAGGCAAGCTGGTGGTGGGTCATGACCTGAAGCACGACTTCCAGGCACTGAAAGAG
GACATGAGCGGCTACACAATCTACGACACGTCCACTGACAGGCTGTTGTGGCGTGAGGCC
AAGCTGGACCACTGCAGGCGTGTCTCCCTGCGGGTGCTGAGTGAGCGCCTCCTGCACAAG
AGCATCCAGAACAGCCTGCTTGGACACAGCTCGGTGGAAGATGCGAGGGCAACGATGGAG
CTCTATCAAATCTCCCAGAGAATCCGAGCCCGCCGAGGGCTGCCCCGCCTGGCTGTGTCA
GACTGA

• Exonuc_X-T (PF00929 )

• None

• None

>Interferon-stimulated gene 20 kDa protein
MAGSREVVAMDCEMVGLGPHRESGLARCSLVNVHGAVLYDKFIRPEGEITDYRTRVSGVT
PQHMVGATPFAVARLEILQLLKGKLVVGHDLKHDFQALKEDMSGYTIYDTSTDRLLWREA
KLDHCRRVSLRVLSERLLHKSIQNSLLGHSSVEDARATMELYQISQRIRARRGLPRLAVS
D

• 1WLJ

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2. Gongora C, David G, Pintard L, Tissot C, Hua TD, Dejean A, Mechti N: Molecular cloning of a new interferon-induced PML nuclear body-associated protein. J Biol Chem. 1997 Aug 1;272(31):19457-63. [PubMed:9235947 ]
3. Pentecost BT: Expression and estrogen regulation of the HEM45 MRNA in human tumor lines and in the rat uterus. J Steroid Biochem Mol Biol. 1998 Jan;64(1-2):25-33. [PubMed:9569007 ]
4. Nguyen LH, Espert L, Mechti N, Wilson DM 3rd: The human interferon- and estrogen-regulated ISG20/HEM45 gene product degrades single-stranded RNA and DNA in vitro. Biochemistry. 2001 Jun 19;40(24):7174-9. [PubMed:11401564 ]
5. Espert L, Degols G, Gongora C, Blondel D, Williams BR, Silverman RH, Mechti N: ISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic viruses. J Biol Chem. 2003 May 2;278(18):16151-8. Epub 2003 Feb 19. [PubMed:12594219 ]