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Identification
HMDB Protein ID HMDBP08890
Secondary Accession Numbers
  • 14618
Name MOSC domain-containing protein 2, mitochondrial
Synonyms Not Available
Gene Name MOSC2
Protein Type Enzyme
Biological Properties
General Function Involved in catalytic activity
Specific Function Catalytic component of the benzamidoxime prodrug- converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex
Pathways Not Available
Reactions Not Available
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
catalytic activity
transition metal ion binding
cofactor binding
pyridoxal phosphate binding
molybdenum ion binding
Cellular Location
  1. Peripheral membrane protein
  2. Mitochondrion outer membrane
Gene Properties
Chromosome Location Chromosome:1
Locus 1q41
SNPs MOSC2
Gene Sequence
>1008 bp
ATGGGCGCTTCCAGCTCCTCCGCGCTGGCCCGCCTCGGCCTCCCAGCCCGGCCCTGGCCC
AGGTGGCTCGGGGTCGCCGCGCTAGGACTGGCCGCCGTGGCCCTGGGGACTGTCGCCTGG
CGCCGCGCATGGCCCAGGCGGCGCCGGCGGCTGCAGCAGGTGGGCACCGTGGCGAAGCTC
TGGATCTACCCGGTGAAATCCTGCAAAGGGGTGCCGGTGAGCGAGGCTGAGTGCACGGCC
ATGGGGCTGCGCAGCGGCAACCTGCGGGACAGGTTTTGGCTGGTGATTAAGGAAGATGGA
CACATGGTCACTGCCCGACAGGAGCCTCGCCTCGTGCTCATCTCCATCATTTATGAGAAT
AACTGCCTGATCTTCAGGGCTCCAGACATGGACCAGCTGGTTTTGCCTAGCAAGCAGCCT
TCCTCAAACAAACTCCACAACTGCAGGATATTTGGCCTTGACATTAAAGGCAGAGACTGT
GGCAATGAGGCAGCTAAGTGGTTCACCAACTTCTTGAAAACTGAAGCGTATAGATTGGTT
CAATTTGAGACAAACATGAAGGGAAGAACATCAAGAAAACTTCTCCCCACTCTTGATCAG
AATTTCCAGGTGGCCTACCCAGACTACTGCCCGCTCCTGATCATGACAGATGCCTCCCTG
GTAGATTTGAATACCAGGATGGAGAAGAAAATGAAAATGGAGAATTTCAGGCCAAATATT
GTGGTGACCGGCTGTGATGCTTTTGAGGAGGATACCTGGGATGAACTCCTAATTGGTAGT
GTAGAAGTGAAAAAGGTAATGGCATGCCCCAGGTGTATTTTGACAACGGTGGACCCAGAC
ACTGGAGTCATAGACAGGAAACAGCCACTGGACACCCTGAAGAGCTACCGCCTGTGTGAT
CCTTCTGAGAGGGAATTGTACAAGTTGTCTCCACTTTTTGGGATCTATTATTCAGTGGAA
AAAATTGGAAGCCTGAGAGTTGGTGACCCTGTGTATCGGATGGTGTAG
Protein Properties
Number of Residues 335
Molecular Weight 38023.0
Theoretical pI 9.5
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>MOSC domain-containing protein 2, mitochondrial
MGASSSSALARLGLPARPWPRWLGVAALGLAAVALGTVAWRRAWPRRRRRLQQVGTVAKL
WIYPVKSCKGVPVSEAECTAMGLRSGNLRDRFWLVIKEDGHMVTARQEPRLVLISIIYEN
NCLIFRAPDMDQLVLPSKQPSSNKLHNCRIFGLDIKGRDCGNEAAKWFTNFLKTEAYRLV
QFETNMKGRTSRKLLPTLDQNFQVAYPDYCPLLIMTDASLVDLNTRMEKKMKMENFRPNI
VVTGCDAFEEDTWDELLIGSVEVKKVMACPRCILTTVDPDTGVIDRKQPLDTLKSYRLCD
PSERELYKLSPLFGIYYSVEKIGSLRVGDPVYRMV
GenBank ID Protein 31542713
UniProtKB/Swiss-Prot ID Q969Z3
UniProtKB/Swiss-Prot Entry Name MOSC2_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_017898.3
GeneCard ID MOSC2
GenAtlas ID MOSC2
HGNC ID HGNC:26064
References
General References
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