Hmdb loader
Identification
HMDB Protein ID HMDBP09017
Secondary Accession Numbers
  • 14758
Name Probable S-adenosyl-L-methionine-dependent methyltransferase METT5D1
Synonyms
  1. Methyltransferase 5 domain-containing protein 1
Gene Name METT5D1
Protein Type Unknown
Biological Properties
General Function Involved in methyltransferase activity
Specific Function Probable S-adenosyl-L-methionine-dependent methyltransferase
Pathways Not Available
Reactions Not Available
GO Classification
Function
catalytic activity
transferase activity
transferase activity, transferring one-carbon groups
methyltransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:1
Locus 11p14.1
SNPs METT5D1
Gene Sequence
>1224 bp
ATGCTTCGGTATCCATATTTTTGTAGAATGTATAAAGAATGCCTTTCATGTTGGTTGGAA
TCTGGCATACCTAATTTAGGTGTCTGGCCAAACAGAATACATACTACAGCAGAAAAATAT
AGAGAATATGAAGCCCGGGAGCAAACAGATCAAACTCAAGCCCAGGAGTTACACAGATCT
CAAGATAGAGATTTTGAAACTATGGCTAAATTACATATTCCAGTAATGGTGGATGAAGTT
GTTCATTGTTTGTCACCACAAAAAGGACAGATTTTTCTAGATATGACATTTGGTTCGGGA
GGGCACACAAAAGCCATTCTGCAGAAGGAGTCAGATATTGTTCTCTATGCCTTGGACAGA
GACCCAACAGCTTATGCATTAGCTGAACATCTTTCAGAGTTGTATCCTAAACAAATCCGA
GCTATGCTGGGCCAGTTCAGCCAGGCAGAAGCCTTATTAATGAAAGCTGGAGTGCAGCCA
GGAACTTTTGATGGAGTTCTTATGGATCTTGGGTGTTCCTCCATGCAACTTGATACTCCT
GAAAGAGGTTTTTCCCTTCGGAAAGATGGCCCTTTGGACATGAGAATGGATGGTGGCAGG
TACCCTGACATGCCCACTGCTGCTGATGTTGTGAATGCTTTAGATCAACAGGCACTTGCA
TCTATCCTAAGAACATACGGGGAGGAGAAGCATGCCAAGAAAATCGCTTCAGCAATTGTT
CAGGCACGCAGCATCTACCCCATCACCAGAACCCAGCAGCTTGCCAGCATCGTTGCAGGA
GCATTTCCTCCCTCTGCTATTTATACACGGAAAGACTTACTACAGCGATCTACCCATATT
GCCACCAAGACTTTCCAGGCTCTTCGCATATTTGTGAACAATGAGCTCAATGAACTCTAC
ACGGGACTGAAGACAGCTCAGAAGTTTCTGAGACCTGGTGGTCGTCTTGTTGCCCTCTCC
TTCCATTCACTAGAGGATCGCATCGTCAAAAGATTTTTGCTTGGAATAAGCATGACAGAA
AGATTTAACCTAAGTGTTAGACAACAAGTGATGAAAACATCTCAATTGGGTTCAGATCAC
GAAAACACGGAAGAAGTCTCTATGAGAAGAGCTCCTTTAATGTGGGAATTGATACACAAG
AAGGTACTTAGTCCACAAGATCAGGATGTACAAGATAACCCCAGAGGGCGCTCAGCCAAG
CTTAGAGCAGCTATCAAATTATAA
Protein Properties
Number of Residues 407
Molecular Weight 46120.6
Theoretical pI 8.85
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Probable S-adenosyl-L-methionine-dependent methyltransferase METT5D1
MLRYPYFCRMYKECLSCWLESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRS
QDRDFETMAKLHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDR
DPTAYALAEHLSELYPKQIRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTP
ERGFSLRKDGPLDMRMDGGRYPDMPTAADVVNALDQQALASILRTYGEEKHAKKIASAIV
QARSIYPITRTQQLASIVAGAFPPSAIYTRKDLLQRSTHIATKTFQALRIFVNNELNELY
TGLKTAQKFLRPGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSVRQQVMKTSQLGSDH
ENTEEVSMRRAPLMWELIHKKVLSPQDQDVQDNPRGRSAKLRAAIKL
GenBank ID Protein 165377209
UniProtKB/Swiss-Prot ID A6NJ78
UniProtKB/Swiss-Prot Entry Name ME5D1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001113528.1
GeneCard ID METT5D1
GenAtlas ID METT5D1
HGNC ID HGNC:26606
References
General References
  1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S: Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004 Jan;36(1):40-5. Epub 2003 Dec 21. [PubMed:14702039 ]
  2. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
  3. Taylor TD, Noguchi H, Totoki Y, Toyoda A, Kuroki Y, Dewar K, Lloyd C, Itoh T, Takeda T, Kim DW, She X, Barlow KF, Bloom T, Bruford E, Chang JL, Cuomo CA, Eichler E, FitzGerald MG, Jaffe DB, LaButti K, Nicol R, Park HS, Seaman C, Sougnez C, Yang X, Zimmer AR, Zody MC, Birren BW, Nusbaum C, Fujiyama A, Hattori M, Rogers J, Lander ES, Sakaki Y: Human chromosome 11 DNA sequence and analysis including novel gene identification. Nature. 2006 Mar 23;440(7083):497-500. [PubMed:16554811 ]