Hmdb loader
Identification
HMDB Protein ID HMDBP09051
Secondary Accession Numbers
  • 14793
Name tRNA wybutosine-synthesizing protein 3 homolog
Synonyms
  1. tRNA-yW-synthesizing protein 3
Gene Name TYW3
Protein Type Unknown
Biological Properties
General Function Involved in methyltransferase activity
Specific Function Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:1
Locus 1p31.1
SNPs TYW3
Gene Sequence
>780 bp
ATGGATCGCAGCGCGGAGTTCAGGAAATGGAAGGCGCAATGTTTGAGCAAAGCGGACCTC
AGCCGGAAGGGCAGTGTTGACGAGGATGTGGTAGAGCTTGTGCAGTTTCTGAACATGCGA
GATCAGTTTTTCACCACCAGCTCCTGCGCTGGCCGCATCCTACTCCTTGACCGGGGTATA
AATGGTTTTGAGGTTCAGAAACAAAACTGTTGCTGGCTACTGGTTACACACAAACTTTGT
GTAAAAGATGATGTGATTGTAGCTCTGAAGAAAGCAAATGGTGATGCCACTTTGAAATTT
GAACCATTTGTTCTTCATGTGCAGTGTCGACAATTGCAGGATGCACAGATTCTGCATTCC
ATGGCAATAGATTCTGGTTTCAGGAACTCTGGCATAACGGTGGGAAAGAGAGGAAAAACT
ATGTTGGCTGTCCGGAGTACACATGGCTTAGAAGTTCCATTAAGCCATAAGGGAAAACTG
ATGGTGACAGAGGAATATATTGACTTCCTGTTAAATGTGGCAAATCAAAAAATGGAGGAA
AACAAGAAAAGAATTGAGAGGTTTTACAACTGCCTACAGCATGCTTTGGAAAGGGAAACG
ATGACTAACTTACATCCCAAGATCAAAGAGAAAAATAACTCATCATATATTCATAAGAAA
AAAAGAAACCCAGAAAAAACACGTGCCCAGTGTATTACTAAAGAAAGTGATGAAGAACTT
GAAAATGATGATGATGATGATCTAGGAATCAATGTTACCATCTTCCCTGAAGATTACTAA
Protein Properties
Number of Residues 259
Molecular Weight 29793.9
Theoretical pI 7.77
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>tRNA wybutosine-synthesizing protein 3 homolog
MDRSAEFRKWKAQCLSKADLSRKGSVDEDVVELVQFLNMRDQFFTTSSCAGRILLLDRGI
NGFEVQKQNCCWLLVTHKLCVKDDVIVALKKANGDATLKFEPFVLHVQCRQLQDAQILHS
MAIDSGFRNSGITVGKRGKTMLAVRSTHGLEVPLSHKGKLMVTEEYIDFLLNVANQKMEE
NKKRIERFYNCLQHALERETMTNLHPKIKEKNNSSYIHKKKRNPEKTRAQCITKESDEEL
ENDDDDDLGINVTIFPEDY
GenBank ID Protein 42734381
UniProtKB/Swiss-Prot ID Q6IPR3
UniProtKB/Swiss-Prot Entry Name TYW3_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_138467.2
GeneCard ID TYW3
GenAtlas ID TYW3
HGNC ID HGNC:24757
References
General References
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