Showing Protein Dual specificity protein phosphatase 14 (HMDBP09423)

• 15301

1. MAP kinase phosphatase 6
2. MKP-1-like protein tyrosine phosphatase
3. MKP-6
4. MKP-L
5. Mitogen-activated protein kinase phosphatase 6

• MAPK signaling pathway

1. Cytoplasmic

>597 bp
ATGAGCTCCAGAGGTCACAGCACGCTACCAAGGACTCTCATGGCCCCTCGGATGATTTCC
GAGGGAGACATAGGAGGCATTGCTCAAATCACCTCCTCTCTATTCCTGGGCAGAGGCAGT
GTGGCCTCCAATCGGCACCTCCTCCAGGCTCGTGGCATCACCTGCATTGTTAATGCTACC
ATTGAGATCCCTAATTTCAACTGGCCCCAATTTGAGTATGTTAAAGTGCCTCTGGCTGAC
ATGCCGCATGCCCCCATTGGACTGTACTTTGACACCGTGGCTGACAAGATCCACAGTGTG
AGCAGGAAGCACGGGGCCACCTTGGTGCACTGTGCTGCAGGGGTGAGCCGCTCAGCCACG
CTGTGTATCGCGTACCTGATGAAATTCCACAACGTGTGCCTGCTGGAGGCATACAACTGG
GTGAAAGCCCGGCGACCTGTCATCAGGCCCAACGTAGGCTTCTGGAGGCAACTGATAGAC
TACGAGCGCCAGCTCTTTGGGAAGTCGACAGTTAAAATGGTACAGACACCTTATGGCATA
GTTCCCGACGTCTATGAGAAGGAGTCCCGACACCTGATGCCTTACTGGGGGATTTAG

• DSPc (PF00782 )

>Dual specificity protein phosphatase 14
MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT
IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT
LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI
VPDVYEKESRHLMPYWGI

• 2WGP

1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
2. Oppermann FS, Gnad F, Olsen JV, Hornberger R, Greff Z, Keri G, Mann M, Daub H: Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics. 2009 Jul;8(7):1751-64. doi: 10.1074/mcp.M800588-MCP200. Epub 2009 Apr 15. [PubMed:19369195 ]
3. Marti F, Krause A, Post NH, Lyddane C, Dupont B, Sadelain M, King PD: Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6. J Immunol. 2001 Jan 1;166(1):197-206. [PubMed:11123293 ]
4. Lountos GT, Tropea JE, Cherry S, Waugh DS: Overproduction, purification and structure determination of human dual-specificity phosphatase 14. Acta Crystallogr D Biol Crystallogr. 2009 Oct;65(Pt 10):1013-20. doi: 10.1107/S0907444909023762. Epub 2009 Sep 16. [PubMed:19770498 ]