Hmdb loader
Identification
HMDB Protein ID HMDBP10022
Secondary Accession Numbers
  • 15963
Name Putative hydroxypyruvate isomerase
Synonyms
  1. Endothelial cell apoptosis protein E-CE1
Gene Name HYI
Protein Type Enzyme
Biological Properties
General Function Carbohydrate transport and metabolism
Specific Function Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity).
Pathways
  • Glyoxylate and dicarboxylate metabolism
Reactions
Hydroxypyruvic acid → Tartronate semialdehyde details
GO Classification
Molecular Function
hydroxypyruvate isomerase activity
Cellular Location Not Available
Gene Properties
Chromosome Location 1
Locus 1p34.2
SNPs HYI
Gene Sequence
>834 bp
ATGGCGCCGCTGCGCTTCTCCGCCAATCTGTCCTGGCTATTCCCCGAGCTCTCCGGCCTC
CCCGCGCGGGTGCGGGCCGCGGGCAGCTCGGGCTTCGAGGCCGTCGAGGTGGCCTGGCCG
TACGCGGAGACGCCTGAGGCGCTGGCGCGCGCCGCGCGAGAAGCGGGGCTGCGGCTTGTA
CTGATCAACACGCCCCCGGGAGACCAAGAGAAGGGGGAAATGGGGCTGGGGGCCGTCCCC
GGGAGACAGGCGGCCTTCCGAGAGGGACTGGAGCAGGCCGTGCGGTATGCCAAAGCCCTG
GGCTGTCCCAGGATCCACCTGATGGCTGGCCGAGTACCCCAGGGAGCTGATCGAATAGCA
GTCAAGGCTGAGATGGAGGCCGTTTTTCTGGAGAACCTGAGGCATGCAGCTGGGGTTTTG
GCTCAGGAGGACCTCGTGGGACTGCTGGAGCCCATCAACACCCGCATCACTGACCCCCAG
TACTTCCTGGACACGCCCCAGCAGGCGGCAGCCATCTTACAGAAGGTAGGAAGACCCAAC
CTCCAATTACAAATGGACATATTCCACTGGCAGATCATGGATGGGAACCTGACAGGAAAC
ATCCGGGAGTTCCTGCCCATTGTTGGGCATGTGCAGGTGGCACAGGTCCCAGGCCGAGGG
GAGCCCAGCAGCCCCGGAGAGCTGAATTTCCCCTATCTGTTTCAACTGCTGGAAGATGAA
GGCTACAAAGGCTTCGTGGGCTGTGAGTATCAGCCTCGAGGAGACACAGTAGAGGGCTTG
AGTTGGCTACGTTCATACTGGGATAGGCGGGGCCACCCAGAGGCTGGCCAGTGA
Protein Properties
Number of Residues 277
Molecular Weight 30405.4
Theoretical pI 5.496
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Putative hydroxypyruvate isomerase
MAPLRFSANLSWLFPELSGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLV
LINTPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIA
VKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPN
LQLQMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEDE
GYKGFVGCEYQPRGDTVEGLSWLRSYWDRRGHPEAGQ
GenBank ID Protein 300068962
UniProtKB/Swiss-Prot ID Q5T013
UniProtKB/Swiss-Prot Entry Name HYI_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001190880.1
GeneCard ID HYI
GenAtlas ID HYI
HGNC ID HGNC:26948
References
General References
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