| Identification |
|---|
| HMDB Protein ID
| HMDBP10091 |
| Secondary Accession Numbers
| |
| Name
| Protein tyrosine phosphatase receptor type D |
| Synonyms
|
Not Available
|
| Gene Name
| PTPRD |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in phosphatase activity |
| Specific Function
| Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Function |
| phosphoprotein phosphatase activity |
| protein tyrosine phosphatase activity |
| hydrolase activity, acting on ester bonds |
| catalytic activity |
| hydrolase activity |
| phosphoric ester hydrolase activity |
| phosphatase activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| dephosphorylation |
| protein amino acid dephosphorylation |
| metabolic process |
| cellular metabolic process |
|
| Cellular Location
|
- Cytoplasmic
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:9 |
| Locus
| 9p23-p24.3 |
| SNPs
| PTPRD |
| Gene Sequence
|
>5739 bp
ATGGTGCACGTAGCCAGGCTGCTGCTGCTGCTCCTCACTTTCTTCCTCCGCACGGATGCT
GAGACACCTCCAAGGTTTACACGAACACCCGTTGATCAGACAGGGGTCTCTGGCGGAGTT
GCCTCTTTCATCTGCCAAGCTACGGGAGACCCAAGACCTAAAATTGTCTGGAACAAAAAA
GGAAAGAAAGTCAGCAATCAGAGATTTGAGGTAATAGAGTTTGACGATGGGTCTGGATCA
GTTCTCAGAATACAACCCTTACGGACTCCGAGGGATGAGGCCATTTATGAATGTGTGGCC
TCAAATAATGTGGGAGAAATAAGTGTATCCACCAGACTCACAGTTTTGCGGGAAGATCAA
ATTCCCAGGGGCTTCCCTACCATTGACATGGGCCCACAGTTGAAGGTGGTTGAGCGTACT
CGCACGGCCACCATGCTTTGTGCAGCCAGTGGTAATCCGGATCCAGAAATCACTTGGTTT
AAAGATTTCTTACCTGTGGACACAAGCAACAACAATGGTCGTATTAAGCAGTTACGATCA
GAATCTATTGGTGGTACACCAATAAGAGGAGCCCTTCAGATTGAGCAGAGTGAAGAGTCT
GACCAAGGAAAATATGAGTGTGTTGCCACCAACAGCGCGGGCACTCGCTATTCCGCTCCT
GCCAATTTATATGTCAGAGAGCTGCGAGAAGTTCGCCGTGTCCCACCAAGATTCTCTATC
CCACCCACTAATCATGAAATCATGCCAGGCGGAAGCGTTAATATCACCTGTGTGGCCGTG
GGGTCACCAATGCCTTATGTAAAGTGGATGTTGGGGGCAGAAGATCTGACACCTGAAGAT
GATATGCCAATAGGAAGAAATGTGCTAGAACTGAATGATGTAAGACAGTCAGCAAATTAC
ACCTGTGTTGCTATGTCAACACTGGGTGTCATTGAAGCAATAGCACAGATCACTGTCAAA
CCCTTACCCAAACCTCCAGGAACTCCTGTAGTGACCGAGAGCACAGCTACAAGCATCACA
CTGACGTGGGACTCTGGGAACCCTGAGCCTGTTTCTTATTACATAATTCAGCATAAACCT
AAAAACTCTGAGGAACTTTACAAAGAAATTGATGGGGTGGCGACCACACGCTACAGTGTC
GCTGGACTAAGTCCCTACTCGGATTATGAATTCAGGGTTGTTGCTGTCAATAACATTGGG
CGGGGGCCTCCCAGCGAACCTGTGCTAACACAAACCTCAGAGCAAGCACCATCCAGTGCC
CCGAGGGATGTCCAGGCACGAATGTTGAGTTCGACCACCATTTTGGTACAGTGGAAGGAA
CCTGAAGAGCCAAATGGACAGATCCAAGGATATAGAGTTTATTATACAATGGATCCCACT
CAACATGTCAACAACTGGATGAAACACAATGTAGCTGACAGCCAAATCACTACTATTGGC
AACTTAGTGCCCCAGAAAACATATTCTGTCAAAGTCCTGGCTTTTACCTCAATTGGAGAT
GGTCCCCTTTCAAGTGACATACAAGTCATCACTCAGACAGGAGTACCAGGGCAGCCACTA
AACTTCAAAGCAGAACCTGAGTCTGAAACAAGTATTTTGCTCTCTTGGACACCTCCACGT
TCAGATACCATTGCCAACTATGAACTGGTCTACAAAGATGGGGAGCATGGAGAGGAGCAA
CGAATTACCATTGAGCCAGGGACATCATATAGGCTGCAAGGACTGAAACCAAACAGCTTA
TACTATTTCCGTCTGGCTGCACGCTCCCCTCAAGGCCTGGGTGCTTCTACTGCAGAAATA
TCAGCTAGAACCATGCAGTCAAAGCCGTCAGCTCCTCCTCAAGACATTAGTTGCACCAGC
CCAAGTTCCACTAGTATTTTGGTAAGTTGGCAACCTCCACCAGTGGAAAAACAGAATGGC
ATTATCACTGAATACTCCATCAAGTACACTGCAGTGGATGGGGAAGATGACAAGCCTCAC
GAGATTTTGGGAATTCCTTCGGACACTACCAAATACCTTTTGGAACAGCTGGAAAAATGG
ACTGAATACCGGATCACTGTGACAGCCCATACAGATGTCGGCCCTGGCCCTGAGAGCTTG
TCCGTGTTGATTCGAACCAATGAAGATGTTCCTAGTGGTCCTCCTCGCAAAGTCGAGGTA
GAGGCTGTCAACTCAACATCTGTTAAAGTCTCATGGCGCTCACCCGTGCCCAATAAACAG
CATGGCCAGATAAGAGGATATCAGGTGCATTATGTGAGGATGGAAAATGGTGAGCCCAAG
GGCCAGCCCATGCTGAAAGATGTCATGCTGGCTGATGCACAGTGGGAATTTGATGATACT
ACTGAACATGACATGATCATTTCTGGGCTCCAGCCTGAAACTTCCTACTCCCTCACCGTC
ACAGCCTACACAACCAAAGGAGATGGTGCTCGCAGCAAGCCCAAACTGGTGTCCACCACT
GGGGCAGTTCCAGGGAAACCTCGGCTTGTGATTAACCACACTCAGATGAATACTGCTCTT
ATTCAGTGGCACCCTCCGGTGGACACATTTGGACCTCTTCAGGGCTACCGTCTAAAATTT
GGCCGCAAGGATATGGAGCCACTTACTACTCTTGAGTTCTCTGAAAAAGAAGATCACTTT
ACAGCTACAGACATCCACAAGGGAGCATCATACGTCTTCAGGCTCTCAGCCAGAAACAAA
GTGGGCTTTGGGGAGGAGATGGTGAAGGAGATTTCCATTCCAGAAGAAGTACCAACTGGA
TTCCCTCAAAACCTTCACTCAGAAGGCACCACTTCAACCTCCGTCCAGTTATCTTGGCAA
CCACCTGTCCTGGCAGAGAGAAATGGCATTATCACCAAGTATACCCTTCTTTATAGGGAT
ATCAACATCCCCCTTCTCCCGATGGAGCAGCTTATTGTTCCAGCTGACACCACTATGACA
CTCACTGGCTTAAAACCAGATACCACATACGATGTAAAAGTACGTGCTCATACGAGCAAA
GGGCCCGGGCCATATAGTCCCAGTGTCCAGTTCAGGACACTGCCTGTGGATCAAGTGTTT
GCAAAAAATTTTCATGTCAAAGCAGTAATGAAGACTTCCGTGTTGCTGTCTTGGGAGATT
CCAGAGAATTATAACTCCGCCATGCCTTTCAAAATTCTTTATGATGATGGGAAAATGGTA
GAAGAAGTGGATGGCCGAGCCACACAGAAGTTAATTGTCAACCTGAAGCCTGAGAAATCA
TATTCATTTGTGCTGACAAATCGTGGAAACAGTGCTGGTGGGCTGCAGCACAGGGTCACG
GCAAAGACTGCACCAGATGTATTACGTACCAAGCCTGCCTTCATTGGGAAGACCAACTTG
GATGGCATGATTACTGTGCAACTGCCTGAAGTACCTGCAAATGAGAATATAAAAGGTTAC
TACATAATAATTGTGCCTTTGAAGAAATCTCGCGGGAAATTTATCAAGCCATGGGAGAGT
CCAGATGAAATGGAATTAGATGAGCTGCTTAAGGAGATATCTAGGAAGCGCAGAAGCATC
CGTTATGGGAGAGAAGTTGAATTAAAGCCATATATTGCCGCTCACTTTGATGTCCTTCCC
ACTGAGTTCACCCTGGGGGATGACAAGCATTATGGTGGATTTACAAACAAGCAACTCCAA
AGTGGTCAAGAATATGTCTTCTTTGTGTTAGCAGTAATGGAACATGCAGAGTCTAAGATG
TATGCAACCAGCCCTTACTCCGACCCCGTGGTGTCAATGGATCTGGATCCGCAGCCAATC
ACGGATGAAGAAGAAGGCTTGATCTGGGTTGTAGGTCCTGTCCTTGCAGTGGTCTTTATC
ATCTGCATTGTCATTGCTATTCTTCTTTATAAAAGGAAGAGGGCAGAGTCCGACTCTAGA
AAAAGCAGCATACCGAACAATAAGGAGATCCCTTCACACCACCCAACAGACCCTGTAGAA
CTGAGGCGCCTTAACTTTCAAACACCGGGTATGGCTAGCCATCCTCCAATACCCATCTTG
GAACTTGCAGACCACATTGAAAGATTGAAAGCAAATGACAACTTGAAGTTTTCCCAGGAA
TATGAGTCAATTGACCCTGGCCAGCAGTTCACTTGGGAACATTCAAACTTGGAAGTAAAC
AAACCAAAGAATAGATACGCGAATGTAATCGCATATGATCATTCCCGGGTTCTCCTATCA
GCTATAGAAGGGATCCCAGGAAGTGACTATGTGAATGCCAACTACATAGATGGGTATAGG
AAGCAAAATGCCTATATTGCAACACAGGGATCTCTCCCCGAAACATTTGGGGACTTTTGG
AGAATGATATGGGAACAACGGAGTGCCACAGTTGTCATGATGACAAAACTAGAAGAAAGA
TCAAGGGTGAAGTGTGACCAGTATTGGCCTAGCAGAGGCACAGAAACCCACGGACTCGTT
CAAGTAACGCTGCTTGATACTGTGGAGCTGGCCACATATTGTGTTCGAACATTTGCACTT
TACAAGAATGGTTCAAGTGAGAAGAGAGAAGTGAGACAATTCCAGTTCACCGCCTGGCCT
GATCATGGTGTTCCAGAACACCCTACACCTTTTCTAGCTTTCTTACGTAGAGTCAAAACC
TGTAACCCTCCCGATGCTGGTCCGATGGTTGTGCACTGCAGTGCGGGAGTTGGCCGGACT
GGTTGCTTCATCGTCATAGATGCCATGTTAGAAAGAATAAAGCATGAAAAAACTGTAGAT
ATTTATGGCCATGTAACTTTAATGAGAGCCCAGAGGAACTATATGGTTCAAACAGAAGAC
CAATACATCTTTATCCATGATGCACTGTTAGAAGCAGTGACTTGTGGAAATACCGAAGTG
CCAGCTAGAAACTTGTATGCCTACATTCAGAAGCTGACACAAATAGAAACGGGAGAGAAT
GTCACAGGAATGGAGCTCGAATTTAAGCGTCTAGCCAGCTCAAAAGCTCACACCTCAAGG
TTTATCAGTGCCAATCTTCCATGTAATAAATTCAAAAATCGCCTTGTTAATATTATGCCA
TATGAATCCACAAGGGTATGCCTGCAGCCTATCCGTGGAGTAGAAGGATCTGATTACATC
AATGCCAGTTTTATTGATGGATACAGACAACAGAAAGCCTACATCGCTACCCAGGGGCCC
TTGGCAGAGACCACTGAAGACTTCTGGCGGATGCTCTGGGAACACAATTCCACCATAGTT
GTGATGCTCACCAAGCTGCGTGAAATGGGCAGAGAGAAATGTCACCAATACTGGCCAGCA
GAACGGTCTGCAAGATACCAGTACTTTGTTGTAGATCCCATGGCTGAGTACAACATGCCA
CAGTATATCCTAAGGGAATTCAAGGTCACAGATGCCAGGGACGGCCAGTCCCGAACAGTA
AGGCAGTTCCAGTTCACTGACTGGCCAGAGCAAGGAGTGCCAAAGTCCGGAGAAGGATTT
ATTGACTTCATCGGCCAAGTCCATAAAACAAAAGAACAGTTTGGCCAAGATGGACCCATT
TCAGTCCATTGCAGCGCGGGCGTTGGAAGAACTGGAGTCTTCATAACGCTAAGCATTGTT
TTGGAAAGAATGAGATATGAAGGAGTTGTAGATATCTTCCAGACTGTCAAAATGTTAAGA
ACACAACGACCAGCTATGGTACAGACAGAGGATCAATATCAGTTTTCCTATCGTGCCGCA
CTAGAGTACCTGGGCAGCTTTGACCACTATGCAACGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 1912 |
| Molecular Weight
| 214784.5 |
| Theoretical pI
| 6.54 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protein tyrosine phosphatase receptor type D
MVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKK
GKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQ
IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRS
ESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSI
PPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANY
TCVAMSTLGVIEAIAQITVKPLPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKP
KNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSA
PRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIG
NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPR
SDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEI
SARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPH
EILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEV
EAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDT
TEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTAL
IQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNK
VGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRD
INIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVF
AKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKS
YSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGY
YIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLP
TEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPI
TDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHPTDPVE
LRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVN
KPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFW
RMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFAL
YKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRT
GCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEV
PARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMP
YESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIV
VMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTV
RQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIV
LERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT
|
| External Links |
|---|
| GenBank ID Protein
| 88687760 |
| UniProtKB/Swiss-Prot ID
| Q2HXI4 |
| UniProtKB/Swiss-Prot Entry Name
| Q2HXI4_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AB211400 |
| GeneCard ID
| PTPRD |
| GenAtlas ID
| PTPRD |
| HGNC ID
| HGNC:9668 |
| References |
|---|
| General References
| Not Available |
