Hmdb loader
Identification
HMDB Protein ID HMDBP10651
Secondary Accession Numbers
  • 16888
Name Glycylpeptide N-tetradecanoyltransferase
Synonyms Not Available
Gene Name NMT2
Protein Type Enzyme
Biological Properties
General Function Involved in glycylpeptide N-tetradecanoyltransferase activity
Specific Function Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins
Pathways Not Available
Reactions Not Available
GO Classification
Function
catalytic activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
acyltransferase activity
n-acyltransferase activity
glycylpeptide n-tetradecanoyltransferase activity
Process
metabolic process
macromolecule metabolic process
protein amino acid lipidation
macromolecule modification
protein modification process
n-terminal protein lipidation
n-terminal protein myristoylation
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:1
Locus 10p13
SNPs NMT2
Gene Sequence
>1458 bp
ATGAGGAGGAGACGGAGCACGCCAAAGGAAGTCCTGGAGGGTATTTGGGAGCCAAAAAGA
AAAAGAAGAAACAGAAGAGAAAAAAGGAGAAACCAAATTCCGGAGGCACCAAGTCAGACT
CGGCATCTGATTCCCAGGAGATTAAAATTCAGCAGCCTTCGAAACACAACACCATCTGGC
AGCAGATTTCAGCGGGAGCAGCCATGGAATCCCAGTGTTCCAATGCAGAAGTTGCAGGAT
ATCCAGAGAGCAATGGAGCTGCTATCCGCATGCCAGGGCCCAGCCAGGAACATTGATGAG
GCTGCAAAGCACAGATACCAGTTTTGGGACACACAACCGGTACCAAAACTAGATGAAGTC
ATAACATCTCATGGTGCAATTGAACCAGATAAAGACAACGTACGCCAAGAACCGTATTCT
TTGCCACAGGGTTTTATGTGGGACACTTTAGACTTGAGTGATGCCGAAGTGCTCAAGGAG
TTATACACGTTGTTAAATGAGAATTACGTAGAAGATGATGACAATATGTTCCGATTTGAC
TATTCACCCGAGTTCCTGTTGTGGGCTCTGCGTCCACCAGGCTGGCTCCTGCAGTGGCAC
TGTGGGGTCAGAGTGTCTTCAAATAAAAAACTGGTCGGGTTCATAAGTGCCATCCCAGCA
AACATTCGGATTTATGACAGTGTGAAGAAGATGGTAGAAATCAACTTTCTTTGTGTTCAT
AAGAAGTTGAGATCGAAACGGGTAGCCCCAGTGCTAATCCGAGAGATCACTAGAAGAGTG
AACCTGGAAGGGATCTTCCAGGCTGTGTACACCGCGGGAGTGGTTCTTCCTAAGCCCATA
GCCACATGCAGATACTGGCATCGATCACTAAACCCCAGAAAATTGGTAGAAGTGAAATTT
TCTCACTTGAGTAGAAATATGACTTTACAGAGAACAATGAAGCTATACAGACTTCCAGAT
GTTACAAAGACTTCAGGTTTGAGACCAATGGAACCAAAAGATATCAAATCAGTTCGAGAA
TTAATCAACACTTACCTGAAGCAGTTTCATCTGGCTCCAGTGATGGATGAAGAGGAAGTA
GCCCACTGGTTCCTCCCCCGGGAGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAAC
GGTAAACTGACTGATTTCCTGAGCTTCTATACGCTCCCCTCCACGGTGATGCACCACCCT
GCTCACAAGAGCCTCAAAGCCGCCTACTCATTCTACAACATCCACACAGAGACGCCCCTG
CTGGACCTCATGAGCGACGCGCTCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAAT
GCACTGGATTTGATGGAAAATAAGACATTCTTGGAAAAACTCAAGTTTGGTATAGGAGAT
GGCAATTTGCAGTATTACCTGTACAATTGGAGGTGTCCAGGTACAGATTCTGAAAAGGTT
GGACTAGTACTACAATAG
Protein Properties
Number of Residues 485
Molecular Weight 56716.1
Theoretical pI 10.02
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Glycylpeptide N-tetradecanoyltransferase
MRRRRSTPKEVLEGIWEPKRKRRNRREKRRNQIPEAPSQTRHLIPRRLKFSSLRNTTPSG
SRFQREQPWNPSVPMQKLQDIQRAMELLSACQGPARNIDEAAKHRYQFWDTQPVPKLDEV
ITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEVLKELYTLLNENYVEDDDNMFRFD
YSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIYDSVKKMVEINFLCVH
KKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPIATCRYWHRSLNPRKLVEVKF
SHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEV
AHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHTETPL
LDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCPGTDSEKV
GLVLQ
GenBank ID Protein 55665860
UniProtKB/Swiss-Prot ID Q5VUC6
UniProtKB/Swiss-Prot Entry Name Q5VUC6_HUMAN
PDB IDs Not Available
GenBank Gene ID AL590365
GeneCard ID NMT2
GenAtlas ID NMT2
HGNC ID HGNC:7858
References
General References Not Available