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Showing Protein Glycylpeptide N-tetradecanoyltransferase (HMDBP10652)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 metabolite
Identification
HMDB Protein ID HMDBP10652
Secondary Accession Numbers
  • 16889
Name Glycylpeptide N-tetradecanoyltransferase
Synonyms Not Available
Gene Name NMT1
Protein Type Enzyme
Biological Properties
General Function Involved in glycylpeptide N-tetradecanoyltransferase activity
Specific Function Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins
Pathways Not Available
Reactions Not Available
GO Classification
Function
catalytic activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
acyltransferase activity
n-acyltransferase activity
glycylpeptide n-tetradecanoyltransferase activity
Process
metabolic process
macromolecule metabolic process
protein amino acid lipidation
macromolecule modification
protein modification process
n-terminal protein lipidation
n-terminal protein myristoylation
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:1
Locus 17q21.31
SNPs NMT1
Gene Sequence 
>551 bp
GCTACTGGGCTGGGCTGCGACCAATGGAAACAAAGGACATTCCAGTAGTGCACCAGCTCC
TCACCAGGTACTTGAAGCAATTTCACCTTACGCCCGTCATGAGCCAGGAGGAGGTGGAGC
ACTGGTTCTACCCCCAGGAGAATATCATCGACACTTTCGTGGTGGAGAACGCAAACGGAG
AGGTGACAGATTTCCTGAGCTTTTATACGCTGCCCTCCACCATCATGAACCATCCAACCC
ACAAGAGTCTCAAAGCTGCTTATTCTTTCTACAACGTTCACACCCAGACCCCTCTTCTAG
ACCTCATGAGCGACGCCCTTGTCCTCGCCAAAATGGTGAGGAGCAGACGGGGGGGTCTCT
GGAGATGTGCAGGGAAGGGGCAGTGGAGCCATGGTGAGCACAGCTCCCGGGACGCGGCCT
CCCATGGGCTGGAGGCTCTGAGCCCTCCTCATCTGTTCTGCTTAGGCAGGGTTCCCGCAG
TTTTTAGGCAGAAACTCAAAACTTGGAGGGAACAAGGAGCATCCGAAGTGAAGGCATTGA
ACTCCTCCTGA
Protein Properties
Number of Residues 182
Molecular Weight 20763.6
Theoretical pI 8.69
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence 
>Glycylpeptide N-tetradecanoyltransferase
YWAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGE
VTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMVRSRRGGLW
RCAGKGQWSHGEHSSRDAASHGLEALSPPHLFCLGRVPAVFRQKLKTWREQGASEVKALN
SS
GenBank ID Protein 133777378
UniProtKB/Swiss-Prot ID A4FU65
UniProtKB/Swiss-Prot Entry Name A4FU65_HUMAN
PDB IDs
GenBank Gene ID BC109226
GeneCard ID NMT1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]