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Identification
HMDB Protein ID HMDBP10743
Secondary Accession Numbers
  • 17005
Name Serine incorporator 1
Synonyms
  1. Tumor differentially expressed protein 1-like
  2. Tumor differentially expressed protein 2
Gene Name SERINC1
Protein Type Unknown
Biological Properties
General Function Involved in L-serine transmembrane transporter activity
Specific Function Enhances the incorporation of serine into phosphatidylserine and sphingolipids
Pathways Not Available
Reactions Not Available
GO Classification
Component
membrane
cell part
Cellular Location
  1. Endoplasmic reticulum membrane
  2. Multi-pass membrane protein
Gene Properties
Chromosome Location Chromosome:6
Locus 6q22.31
SNPs SERINC1
Gene Sequence
>1362 bp
ATGGGGAGCGTCCTGGGGCTGTGCTCCATGGCGAGCTGGATACCATGTTTGTGTGGAAGT
GCCCCGTGTTTGCTATGCCGATGCTGTCCTAGTGGAAACAACTCCACTGTAACTAGATTG
ATCTATGCACTTTTCTTGCTTGTTGGAGTATGTGTAGCTTGTGTAATGTTGATACCAGGA
ATGGAAGAACAACTGAATAAGATTCCTGGATTTTGTGAGAATGAGAAAGGTGTTGTCCCT
TGTAACATTTTGGTTGGCTATAAAGCTGTATATCGTTTGTGCTTTGGTTTGGCTATGTTC
TATCTTCTTCTCTCTTTACTAATGATCAAAGTGAAGAGTAGCAGTGATCCTAGAGCTGCA
GTGCACAATGGATTTTGGTTCTTTAAATTTGCTGCAGCAATTGCAATTATTATTGGGGCA
TTCTTCATTCCAGAAGGAACTTTTACAACTGTGTGGTTTTATGTAGGCATGGCAGGTGCC
TTTTGTTTCATCCTCATACAACTAGTCTTACTTATTGATTTTGCACATTCATGGAATGAA
TCGTGGGTTGAAAAAATGGAAGAAGGGAACTCGAGATGTTGGTATGCAGCCTTGTTATCA
GCTACAGCTCTGAATTATCTGCTGTCTTTAGTTGCTATCGTCCTGTTCTTTGTCTACTAC
ACTCATCCAGCCAGTTGTTCAGAAAACAAGGCGTTCATCAGTGTCAACATGCTCCTCTGC
GTTGGTGCTTCTGTAATGTCTATACTGCCAAAAATCCAAGAATCACAACCAAGATCTGGT
TTGTTACAGTCTTCAGTAATTACAGTCTACACAATGTATTTGACATGGTCAGCTATGACC
AATGAACCAGAAACAAATTGCAACCCAAGTCTACTAAGCATAATTGGCTACAATACAACA
AGCACTGTCCCAAAGGAAGGGCAGTCAGTCCAGTGGTGGCATGCTCAAGGAATTATAGGA
CTAATTCTCTTTTTGTTGTGTGTATTTTATTCCAGCATCCGTACTTCAAACAATAGTCAG
GTTAATAAACTGACTCTAACAAGTGATGAATCTACATTAATAGAAGATGGTGGAGCTAGA
AGTGATGGATCACTGGAGGATGGGGACGATGTTCACCGAGCTGTAGATAATGAAAGGGAT
GGTGTCACTTACAGTTATTCCTTCTTTCACTTCATGCTTTTCCTGGCTTCACTTTATATC
ATGATGACCCTTACCAACTGGTACAGGTATGAACCCTCTCGTGAGATGAAAAGTCAGTGG
ACAGCTGTCTGGGTGAAAATCTCTTCCAGTTGGATTGGCATCGTGCTGTATGTTTGGACA
CTCGTGGCACCACTTGTTCTTACAAATCGTGATTTTGACTGA
Protein Properties
Number of Residues 453
Molecular Weight 50494.4
Theoretical pI 5.65
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • 89-109
  • 124-144
  • 152-172
  • 198-218
  • 232-252
  • 260-280
  • 310-330
  • 388-408
  • 427-447
Protein Sequence
>Serine incorporator 1
MGSVLGLCSMASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPG
MEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAA
VHNGFWFFKFAAAIAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNE
SWVEKMEEGNSRCWYAALLSATALNYLLSLVAIVLFFVYYTHPASCSENKAFISVNMLLC
VGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGYNTT
STVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGGAR
SDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQW
TAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD
GenBank ID Protein 24308213
UniProtKB/Swiss-Prot ID Q9NRX5
UniProtKB/Swiss-Prot Entry Name SERC1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_020755.2
GeneCard ID SERINC1
GenAtlas ID SERINC1
HGNC ID HGNC:13464
References
General References
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