| Identification |
|---|
| HMDB Protein ID
| HMDBP10890 |
| Secondary Accession Numbers
| |
| Name
| Metallothionein-1L |
| Synonyms
|
- MT-1L
- MT-IL
- Metallothionein-IL
|
| Gene Name
| MT1L |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Involved in metal ion binding |
| Specific Function
| Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 16q13 |
| SNPs
| MT1L |
| Gene Sequence
|
>186 bp
ATGGACCCCAACTGCTCGTGCGCCACTGGGGGCTCCTGCTCCTGTGCCAGCTCCTGCAAG
TGCAAAGAGTGCAAATGTACCTCCTGCAAGAAGAGCTGCTGCTCCTGCTGCCCCATGGGC
TGTGCCAAGTGTGCCCAGGGCTGCGTCTGCAAAGGGGCGTCGGAGAAGTGCAGCTGCTGT
GCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 61 |
| Molecular Weight
| 6062.1 |
| Theoretical pI
| 8.0 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Metallothionein-1L
MDPNCSCATGGSCSCASSCKCKECKCTSCKKSCCSCCPMGCAKCAQGCVCKGASEKCSCC
A
|
| External Links |
|---|
| GenBank ID Protein
| 1495464 |
| UniProtKB/Swiss-Prot ID
| Q93083 |
| UniProtKB/Swiss-Prot Entry Name
| MT1L_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| X97261 |
| GeneCard ID
| MT1L |
| GenAtlas ID
| MT1L |
| HGNC ID
| HGNC:7404 |
| References |
|---|
| General References
| - Lambert E, Kille P, Swaminathan R: Cloning and sequencing a novel metallothionein I isoform expressed in human reticulocytes. FEBS Lett. 1996 Jul 1;389(2):210-2. [PubMed:8766831 ]
|
