Hmdb loader
Identification
HMDB Protein ID HMDBP11381
Secondary Accession Numbers
  • 17710
Name Acyl-CoA-binding domain-containing protein 6
Synonyms Not Available
Gene Name ACBD6
Protein Type Unknown
Biological Properties
General Function Involved in acyl-CoA binding
Specific Function Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0- CoA. Does not bind fatty acids
Pathways Not Available
Reactions Not Available
GO Classification
Function
binding
fatty acid binding
acyl-coa binding
lipid binding
Cellular Location
  1. Cytoplasm
Gene Properties
Chromosome Location Chromosome:1
Locus 1q25.1
SNPs ACBD6
Gene Sequence
>849 bp
ATGGCTTCATCATTCCTGCCCGCGGGGGCCATCACCGGCGACAGCGGTGGAGAGCTGAGC
TCAGGGGACGACTCCGGGGAGGTGGAGTTCCCCCATAGCCCTGAGATCGAGGAGACCAGT
TGCCTGGCCGAGCTGTTTGAGAAGGCTGCCGCGCACCTGCAAGGCCTGATTCAGGTGGCC
AGCAGGGAGCAGCTCTTGTACCTGTATGCCAGGTACAAACAGGTCAAAGTTGGAAATTGT
AATACTCCTAAACCAAGCTTCTTTGATTTTGAAGGAAAGCAAAAATGGGAAGCTTGGAAA
GCACTTGGTGATTCAAGCCCCAGCCAAGCAATGCAGGAATATATCGCAGTAGTTAAAAAA
CTAGATCCAGGTTGGAATCCTCAGATACCAGAGAAGAAAGGAAAAGAAGCAAATACAGGT
TTTGGTGGGCCAGTTATTAGTTCTCTATATCATGAAGAAACCATCAGGGAAGAAGACAAA
AATATATTTGATTACTGCAGGGAAAACAACATTGACCATATAACCAAAGCCATCAAATCG
AAAAATGTGGATGTGAATGTGAAAGATGAAGAGGGTAGGGCTCTACTTCACTGGGCCTGT
GATCGAGGACATAAGGAACTAGTCACAGTGTTGCTGCAACATAGAGCTGACATTAACTGT
CAGGACAATGAAGGCCAAACAGCTCTACATTATGCCTCTGCCTGTGAGTTTCTGGATATT
GTAGAGCTGCTGCTCCAGTCTGGTGCTGACCCCACTCTCCGAGACCAGGATGGCTGCCTG
CCAGAGGAGGTGACAGGCTGCAAAACAGTTTCTTTGGTGCTGCAGCGGCACACAACTGGC
AAGGCTTAA
Protein Properties
Number of Residues 282
Molecular Weight 31150.6
Theoretical pI 4.76
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Acyl-CoA-binding domain-containing protein 6
MASSFLPAGAITGDSGGELSSGDDSGEVEFPHSPEIEETSCLAELFEKAAAHLQGLIQVA
SREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKK
LDPGWNPQIPEKKGKEANTGFGGPVISSLYHEETIREEDKNIFDYCRENNIDHITKAIKS
KNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDI
VELLLQSGADPTLRDQDGCLPEEVTGCKTVSLVLQRHTTGKA
GenBank ID Protein 56204928
UniProtKB/Swiss-Prot ID Q9BR61
UniProtKB/Swiss-Prot Entry Name ACBD6_HUMAN
PDB IDs Not Available
GenBank Gene ID AL139141
GeneCard ID ACBD6
GenAtlas ID ACBD6
HGNC ID HGNC:23339
References
General References
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  2. Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K, Spencer CC, Jones MC, Gillson C, Searle S, Zhou Y, Kokocinski F, McDonald L, Evans R, Phillips K, Atkinson A, Cooper R, Jones C, Hall RE, Andrews TD, Lloyd C, Ainscough R, Almeida JP, Ambrose KD, Anderson F, Andrew RW, Ashwell RI, Aubin K, Babbage AK, Bagguley CL, Bailey J, Beasley H, Bethel G, Bird CP, Bray-Allen S, Brown JY, Brown AJ, Buckley D, Burton J, Bye J, Carder C, Chapman JC, Clark SY, Clarke G, Clee C, Cobley V, Collier RE, Corby N, Coville GJ, Davies J, Deadman R, Dunn M, Earthrowl M, Ellington AG, Errington H, Frankish A, Frankland J, French L, Garner P, Garnett J, Gay L, Ghori MR, Gibson R, Gilby LM, Gillett W, Glithero RJ, Grafham DV, Griffiths C, Griffiths-Jones S, Grocock R, Hammond S, Harrison ES, Hart E, Haugen E, Heath PD, Holmes S, Holt K, Howden PJ, Hunt AR, Hunt SE, Hunter G, Isherwood J, James R, Johnson C, Johnson D, Joy A, Kay M, Kershaw JK, Kibukawa M, Kimberley AM, King A, Knights AJ, Lad H, Laird G, Lawlor S, Leongamornlert DA, Lloyd DM, Loveland J, Lovell J, Lush MJ, Lyne R, Martin S, Mashreghi-Mohammadi M, Matthews L, Matthews NS, McLaren S, Milne S, Mistry S, Moore MJ, Nickerson T, O'Dell CN, Oliver K, Palmeiri A, Palmer SA, Parker A, Patel D, Pearce AV, Peck AI, Pelan S, Phelps K, Phillimore BJ, Plumb R, Rajan J, Raymond C, Rouse G, Saenphimmachak C, Sehra HK, Sheridan E, Shownkeen R, Sims S, Skuce CD, Smith M, Steward C, Subramanian S, Sycamore N, Tracey A, Tromans A, Van Helmond Z, Wall M, Wallis JM, White S, Whitehead SL, Wilkinson JE, Willey DL, Williams H, Wilming L, Wray PW, Wu Z, Coulson A, Vaudin M, Sulston JE, Durbin R, Hubbard T, Wooster R, Dunham I, Carter NP, McVean G, Ross MT, Harrow J, Olson MV, Beck S, Rogers J, Bentley DR, Banerjee R, Bryant SP, Burford DC, Burrill WD, Clegg SM, Dhami P, Dovey O, Faulkner LM, Gribble SM, Langford CF, Pandian RD, Porter KM, Prigmore E: The DNA sequence and biological annotation of human chromosome 1. Nature. 2006 May 18;441(7091):315-21. [PubMed:16710414 ]
  3. Soupene E, Serikov V, Kuypers FA: Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells. J Lipid Res. 2008 May;49(5):1103-12. doi: 10.1194/jlr.M800007-JLR200. Epub 2008 Feb 11. [PubMed:18268358 ]