Hmdb loader
Identification
HMDB Protein ID HMDBP11501
Secondary Accession Numbers
  • 17855
Name Alpha-catulin
Synonyms
  1. ACRP
  2. Alpha-catenin-related protein
  3. Catenin alpha-like protein 1
Gene Name CTNNAL1
Protein Type Unknown
Biological Properties
General Function Involved in structural molecule activity
Specific Function May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1)
Pathways Not Available
Reactions Not Available
GO Classification
Component
cytoskeleton
organelle
non-membrane-bounded organelle
intracellular non-membrane-bounded organelle
actin cytoskeleton
Function
binding
structural molecule activity
protein binding
cell adhesion molecule binding
cadherin binding
Process
cell adhesion
cellular process
Cellular Location
  1. Cell membrane
  2. Cytoplasm
  3. Peripheral membrane protein
  4. cytoskeleton
Gene Properties
Chromosome Location Chromosome:9
Locus 9q31.2
SNPs CTNNAL1
Gene Sequence
>2205 bp
ATGGCCGCCTCTCCCGGACCCGCCGGCGTTGGCGGCGCCGGAGCAGTCTACGGCTCCGGC
TCTTCGGGCTTCGCCCTCGACTCGGGACTGGAGATCAAAACTCGCTCGGTGGAGCAGACG
CTACTCCCGCTGGTTTCTCAGATCACCACGCTTATTAATCATAAAGATAATACCAAAAAG
TCCGATAAAACTCTGCAAGCAATTCAGCGTGTAGGACAAGCTGTCAACTTGGCAGTTGGA
AGATTTGTTAAAGTAGGAGAAGCTATAGCCAATGAAAACTGGGATTTGAAAGAAGAAATA
AATATTGCTTGTATTGAAGCTAAACAAGCAGGAGAAACAATTGCAGCACTTACAGACATA
ACCAACTTGAACCATCTGGAATCTGATGGGCAGATCACAATTTTTACAGACAAAACAGGA
GTGATAAAGGCTGCAAGATTACTTCTTTCTTCAGTGACAAAAGTGTTGTTGCTGGCAGAC
CGAGTAGTCATTAAACAGATAATAACATCAAGAAATAAGGTTCTCGCAACTATGGAAAGA
CTAGAGAAAGTGAATAGCTTTCAAGAGTTTGTCCAAATATTCAGTCAATTTGGAAATGAA
ATGGTGGAGTTTGCACATCTGAGTGGAGATAGACAAAATGATTTGAAAGATGAAAAGAAA
AAGGCAAAAATGGCAGCAGCTAGGGCAGTTCTTGAAAAGTGTACAATGATGCTTCTCACT
GCTTCAAAGACATGTCTGAGGCATCCTAACTGCGAATCAGCCCATAAAAACAAAGAAGGA
GTATTTGACCGTATGAAAGTGGCATTGGATAAGGTCATTGAAATTGTGACTGACTGTAAA
CCGAATGGAGAGACTGACATTTCATCTATCAGTATTTTTACTGGAATTAAGGAATTCAAG
ATGAATATTGAAGCTCTTCGGGAGAATCTTTATTTTCAGTCCAAAGAGAACCTTTCTGTG
ACATTGGAAGTCATCTTGGAGCGTATGGAGGACTTTACTGATTCTGCCTACACCAGCCAT
GAGCACAGAGAACGCATCTTGGAACTGTCAACTCAGGCGAGAATGGAACTGCAGCAGTTA
ATTTCTGTGTGGATTCAAGCTCAAAGCAAGAAAACAAAAAGCATCGCTGAAGAACTGGAA
CTCAGTATTTTGAAAATCAGTCACAGTCTTAATGAACTTAAGAAAGAACTTCATAGTACA
GCGACACAGCTGGCAGCAGATCTATTAAAATACCATGCTGATCATGTGGTTCTAAAAGCA
TTAAAACTTACTGGAGTAGAAGGAAATTTAGAAGCTTTGGCTGAATATGCCTGTAAACTC
TCTGAACAGAAAGAGCAGCTTGTTGAGACCTGTCGATTGTTACGACACATATCTGGGACA
GAACCTCTGGAAATAACCTGTATACATGCAGAGGAGACATTTCAGGTGACTGGCCAACAG
ATAATTTCTGCTGCTGAAACATTGACATTGCATCCATCTAGTAAAATTGCTAAAGAAAAC
CTAGATGTATTTTGTGAAGCTTGGGAATCCCAAATTAGTGACATGTCAACACTGCTGAGA
GAAATCAATGACGTGTTTGAAGGGAGACGAGGAGAGAAGTATGGCTACCTTTCACTTCCA
AAGCCAATGAAGAATAATGCAAACCTGAAATCATTAAAGCCAGACAAGCCTGACTCTGAG
GAGCAAGCCAAGATAGCAAAGCTTGGACTTAAGCTGGGTTTGCTCACCTCTGACGCTGAC
TGCGAAATTGAGAAGTGGGAAGATCAGGAGAATGAGATTGTTCAATATGGACGGAACATG
TCCAGTATGGCCTATTCTCTGTATTTATTCACTAGAGGAGAGGGGCCACTGAAAACTTCC
CAGGATTTAATTCATCAACTAGAGGTTTTTGCTGCAGAGGGTTTAAAGCTTACTTCCAGT
GTTCAAGCTTTTTCAAAACAGCTGAAAGACGATGACAAGCTTATGCTTCTCCTGGAAATA
AACAAGCTAATTCCTCTATGCCACCAGCTCCAGACAGTAACTAAGACTTCTTTGCAGAAT
AAAGTATTTCTAAAGGTTGACAAGTGTATTACGAAGACAAGATCCATGATGGCTCTCTTA
GTCCAACTTCTTTCACTTTGTTATAAACTGCTGAAGAAGCTTCAGATGGAAAATAACGGA
TGGGTCTCAGTTACAAATAAGGACACTATGGATAGTAAAACTTAA
Protein Properties
Number of Residues 734
Molecular Weight 81895.6
Theoretical pI 6.62
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Alpha-catulin
MAASPGPAGVGGAGAVYGSGSSGFALDSGLEIKTRSVEQTLLPLVSQITTLINHKDNTKK
SDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDI
TNLNHLESDGQITIFTDKTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMER
LEKVNSFQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLT
ASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSISIFTGIKEFK
MNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQL
ISVWIQAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKA
LKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQ
IISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLP
KPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNM
SSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDDKLMLLLEI
NKLIPLCHQLQTVTKTSLQNKVFLKVDKCITKTRSMMALLVQLLSLCYKLLKKLQMENNG
WVSVTNKDTMDSKT
GenBank ID Protein 197692267
UniProtKB/Swiss-Prot ID Q9UBT7
UniProtKB/Swiss-Prot Entry Name CTNL1_HUMAN
PDB IDs Not Available
GenBank Gene ID AB451283
GeneCard ID CTNNAL1
GenAtlas ID CTNNAL1
HGNC ID HGNC:2512
References
General References
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