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Identification
HMDB Protein ID HMDBP11632
Secondary Accession Numbers None
Name Ceramide synthase 4
Synonyms
  1. CerS4
  2. LAG1 longevity assurance homolog 4
Gene Name CERS4
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner (By similarity).
Pathways
  • sphingolipid metabolism
Reactions
Acyl-CoA + Sphingosine → Coenzyme A + N-Acylsphingosine details
Acyl-CoA + Sphinganine → Coenzyme A + Dihydroceramide details
GO Classification
Biological Process
small molecule metabolic process
ceramide biosynthetic process
phospholipid metabolic process
sphingolipid biosynthetic process
Cellular Component
endoplasmic reticulum membrane
nuclear membrane
integral to membrane
Molecular Function
sphingosine N-acyltransferase activity
sequence-specific DNA binding
sequence-specific DNA binding transcription factor activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight Not Available
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9HA82
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:23747
References
General References Not Available