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HMDB Protein ID HMDBP11635
Secondary Accession Numbers None
Name Chitinase-3-like protein 1
  1. 39 kDa synovial protein
  2. Cartilage glycoprotein 39
  3. YKL-40
  4. CGP-39
  5. GP-39
  6. hCGP-39
Gene Name CHI3L1
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Carbohydrate-binding lectin with a preference for chitin. May play a role in defense against pathogens, or in tissue remodeling. May play an important role in the capacity of cells to respond to and cope with changes in their environment.
  • Amino sugar and nucleotide sugar metabolism
Chitin + Water → N-Acetyl-D-glucosamine + Chitin details
Chitin + Water → N-Acetyl-D-glucosaminide + Chitin details
GO Classification
Biological Process
response to interleukin-1
response to interleukin-6
response to mechanical stimulus
inflammatory response
cellular response to tumor necrosis factor
activation of NF-kappaB-inducing kinase activity
cellular response to interleukin-1
chitin catabolic process
interleukin-8 secretion
positive regulation of angiogenesis
positive regulation of ERK1 and ERK2 cascade
positive regulation of peptidyl-threonine phosphorylation
positive regulation of protein kinase B signaling cascade
cartilage development
lung development
carbohydrate metabolic process
Cellular Component
endoplasmic reticulum
proteinaceous extracellular matrix
extracellular space
Molecular Function
cation binding
chitin binding
extracellular matrix structural constituent
hydrolase activity, hydrolyzing O-glycosyl compounds
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight Not Available
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P36222
UniProtKB/Swiss-Prot Entry Name Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
General References Not Available