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Identification
HMDB Protein ID HMDBP11713
Secondary Accession Numbers None
Name Dolichol phosphate-mannose biosynthesis regulatory protein
Synonyms Not Available
Gene Name DPM2
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Regulates the biosynthesis of dolichol phosphate-mannose. Essential for the ER localization and stable expression of DPM1.
Pathways
  • Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
  • N-Glycan biosynthesis
Reactions
Guanosine diphosphate mannose + Dolichol-20 → Guanosine diphosphate + Dolichyl phosphate D-mannose details
UDP-N-acetyl-D-glucosamine + 1-Phosphatidyl-D-myo-inositol → UDP + details
GO Classification
Biological Process
dolichol-linked oligosaccharide biosynthetic process
protein N-linked glycosylation via asparagine
C-terminal protein lipidation
protein O-linked mannosylation
preassembly of GPI anchor in ER membrane
regulation of protein stability
Cellular Component
endoplasmic reticulum membrane
integral to endoplasmic reticulum membrane
dolichol-phosphate-mannose synthase complex
glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight Not Available
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID O94777
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:3006
References
General References Not Available