Human Metabolome Database: Showing Protein Dual specificity protein phosphatase 23 (HMDBP11722)

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Identification Biological properties Gene properties Protein properties External links References XML Show 2 metabolites

Identification

HMDB Protein ID

HMDBP11722

Secondary Accession Numbers

None

Name

Dual specificity protein phosphatase 23

Synonyms

Low molecular mass dual specificity phosphatase 3
VH1-like phosphatase Z
LDP-3

Gene Name

DUSP23

Protein Type

Unknown

Biological Properties

General Function

Not Available

Specific Function

Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).

Pathways

Not Available

Reactions

Protein tyrosine phosphate + Water → protein tyrosine + Phosphate	details
A phosphoprotein + Water → a protein + Phosphate	details

GO Classification

Biological Process
peptidyl-tyrosine dephosphorylation
Cellular Component
cytosol
nucleus
Molecular Function
protein tyrosine/serine/threonine phosphatase activity
protein tyrosine phosphatase activity

Cellular Location

Not Available

Gene Properties

Chromosome Location

Locus

1q23.2

SNPs

Not Available

Gene Sequence

Not Available

Protein Properties

Number of Residues

Not Available

Molecular Weight

16587.985

Theoretical pI

8.213

Pfam Domain Function

Not Available

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>>gi|56786144|ref|NP_060293.2| dual specificity protein phosphatase 23 [Homo sapiens]
MGVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHR
LRIPDFCPPA

External Links

GenBank ID Protein

Not Available

UniProtKB/Swiss-Prot ID

Q9BVJ7

UniProtKB/Swiss-Prot Entry Name

Not Available

PDB IDs