| Identification |
|---|
| HMDB Protein ID
| HMDBP11773 |
| Secondary Accession Numbers
| None |
| Name
| Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 1 |
| Synonyms
|
- 3-hydroxyacyl-CoA dehydratase 1
- Cementum attachment protein
- Protein-tyrosine phosphatase-like member A
- HACD1
|
| Gene Name
| PTPLA |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Responsible for the dehydration step in very long-chain fatty acid (VLCFA) synthesis.
|
| Pathways
|
- Biosynthesis of unsaturated fatty acids
- Fatty acid elongation
|
| Reactions
|
| A very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] → a very-long-chain trans-2,3-dehydroacyl-[acyl-carrier protein] + Water |
details
|
|
| GO Classification
|
| Biological Process |
| multicellular organismal development |
| signal transduction |
| fatty acid biosynthetic process |
| Cellular Component |
| endoplasmic reticulum membrane |
| integral to membrane |
| Molecular Function |
| lyase activity |
| protein tyrosine phosphatase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| 10p14-p13 |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 32387.485 |
| Theoretical pI
| 9.035 |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>>gi|82659105|ref|NP_055056.3| very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 1 [Homo sapiens]
MGRLTEAAAAGSGSRAAGWAGSPPTLLPLSPTSPRCAATMASSDEDGTNGGASEAGEDRE
APGERRRLGV
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| B0YJ81 |
| UniProtKB/Swiss-Prot Entry Name
| Not Available |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| HGNC:9639 |
| References |
|---|
| General References
| Not Available |
