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HMDB Protein ID HMDBP11785
Secondary Accession Numbers None
Name Inactive heparanase-2
  1. Hpa2
Gene Name HPSE2
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro).
  • Glycosaminoglycan degradation
  • Proteoglycans in cancer
Heparan sulfate + Water → Heparan sulfate + details
GO Classification
Biological Process
small molecule metabolic process
glycosaminoglycan catabolic process
carbohydrate metabolic process
Cellular Component
plasma membrane
proteinaceous extracellular matrix
Molecular Function
cation binding
heparan sulfate proteoglycan binding
heparanase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight Not Available
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q8WWQ2
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
General References Not Available