Hmdb loader
HMDB Protein ID HMDBP12027
Secondary Accession Numbers None
Name Palmitoyltransferase ZDHHC3
  1. Protein DHHC1
  2. Zinc finger DHHC domain-containing protein 3
  3. Zinc finger protein 373
  4. DHHC-3
Gene Name ZDHHC3
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi (By similarity).
Pathways Not Available
Palmityl-CoA + protein-cysteine → S-palmitoyl protein + Coenzyme A details
GO Classification
Biological Process
protein palmitoylation
protein targeting
Cellular Component
integral to membrane
Golgi membrane
Molecular Function
metal ion binding
zinc ion binding
palmitoyltransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location 3
Locus 3p21.31
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight 34170.15
Theoretical pI 8.183
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>>gi|206597477|ref|NP_001128651.1| palmitoyltransferase ZDHHC3 isoform 1 [Homo sapiens]
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9NYG2
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
General References Not Available