Human Metabolome Database: Showing Protein Neuronal acetylcholine receptor subunit alpha-4 (HMDBP12050)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 metabolite

Identification
HMDB Protein ID	HMDBP12050
Secondary Accession Numbers	None
Name	Neuronal acetylcholine receptor subunit alpha-4
Synonyms	Not Available
Gene Name	CHRNA4
Protein Type	Unknown
Biological Properties
General Function	Involved in neurotransmitter receptor activity
Specific Function	After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane
Pathways	3-Methylthiofentanyl Action Pathway Alfentanil Action Pathway Alvimopan Action Pathway Anileridine Action Pathway Benzocaine Action Pathway Bupivacaine Action Pathway Buprenorphine Action Pathway Carfentanil Action Pathway Chloroprocaine Action Pathway Citalopram Action Pathway Cocaine Action Pathway Codeine Action Pathway Desipramine Action Pathway Dezocine Action Pathway Dibucaine Action Pathway Dihydromorphine Action Pathway Dimethylthiambutene Action Pathway Diphenoxylate Action Pathway Escitalopram Action Pathway Ethylmorphine Action Pathway Fentanyl Action Pathway Fluoxetine Action Pathway Heroin Action Pathway Hydrocodone Action Pathway Hydromorphone Action Pathway Imipramine Action Pathway Ketobemidone Action Pathway Levallorphan Action Pathway Levobupivacaine Action Pathway Levomethadyl Acetate Action Action Pathway Levorphanol Action Pathway Lidocaine (Local Anaesthetic) Action Pathway Mepivacaine Action Pathway Methadone Action Pathway Methadyl Acetate Action Pathway Morphine Action Pathway Nalbuphine Action Pathway Naloxone Action Pathway Naltrexone Action Pathway Nicotine Action Pathway Nicotine Metabolism Pathway Oxybuprocaine Action Pathway Oxycodone Action Pathway Oxymorphone Action Pathway Pentazocine Action Pathway Prilocaine Action Pathway Procaine Action Pathway Proparacaine Action Pathway Propoxyphene Action Pathway Remifentanil Action Pathway Ropivacaine Action Pathway Sufentanil Action Pathway Tramadol Action Action Pathway
Reactions	Not Available
GO Classification	Not Available
Cellular Location	Not Available
Gene Properties
Chromosome Location	Not Available
Locus	20q13.2-q13.3
SNPs	CHRNA4
Gene Sequence	Not Available
Protein Properties
Number of Residues	627
Molecular Weight	69958.0
Theoretical pI	7.21
Pfam Domain Function	Not Available
Signals	Not Available
Transmembrane Regions	243-267↵275-293↵309-330↵601-619
Protein Sequence	Not Available
External Links
GenBank ID Protein	755648
UniProtKB/Swiss-Prot ID	P43681
UniProtKB/Swiss-Prot Entry Name	ACHA4_HUMAN
PDB IDs	Not Available
GenBank Gene ID	L35901
GeneCard ID	CHRNA4
GenAtlas ID	CHRNA4
HGNC ID	HGNC:1958
References
General References	Not Available