Hmdb loader
Identification
HMDB Protein ID HMDBP12138
Secondary Accession Numbers None
Name Nuclear envelope phosphatase-regulatory subunit 1
Synonyms
  1. NEP1-R1
  2. Transmembrane protein 188
Gene Name CNEP1R1
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol.
Pathways Not Available
Reactions Not Available
GO Classification
Biological Process
positive regulation of protein dephosphorylation
positive regulation of triglyceride biosynthetic process
mitotic nuclear envelope disassembly
lipid metabolic process
protein localization to nucleus
Cellular Component
cytosol
cytoplasm
nuclear envelope
nuclear membrane
integral to membrane
Nem1-Spo7 phosphatase complex
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 125
Molecular Weight 14266.57
Theoretical pI 8.386
Pfam Domain Function
Signals Not Available
Transmembrane Regions
  • 33-53;65-85;
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q8N9A8
UniProtKB/Swiss-Prot Entry Name NEPR1_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
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