| Identification |
|---|
| HMDB Protein ID
| HMDBP12148 |
| Secondary Accession Numbers
| None |
| Name
| Beta-fibrinogenase jerdofibrase |
| Synonyms
|
- Snake venom serine protease
- SVSP
|
| Gene Name
| Not Available |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Fibrin(ogen)olytic serine protease degrades Bbeta-chain of human fibrinogen (FGB) and shows a lower activity on Aa-chain (FGA). Also degrades fibrin directly. Releases fibrinopeptide B and a small amount of fibrinopeptide A. Has also be shown to catalyze the hydrolysis of some chromogenic substrates such as S2238, S2160, S2302 and S2251. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Cellular Component |
| extracellular region |
| Molecular Function |
| toxin activity |
| serine-type peptidase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 2294.595 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P0DMU1 |
| UniProtKB/Swiss-Prot Entry Name
| VSPJF_PROJR |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Jin Y, Lu QM, Wei JF, Li DS, Wang WY, Xiong YL: Purification and characterization of jerdofibrase, a serine protease from the venom of Trimeresurus jerdonii snake. Toxicon. 2001 Aug;39(8):1203-10. doi: 10.1016/s0041-0101(00)00261-0. [PubMed:11306131 ]
- Jin Y, Lu QM, Wang WY, Xiong YL: Actions of two serine proteases from Trimeresurus jerdonii venom on chromogenic substrates and fibrinogen. Comp Biochem Physiol B Biochem Mol Biol. 2002 Jul;132(3):529-34. doi: 10.1016/s1096-4959(02)00069-6. [PubMed:12091097 ]
|
