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Identification
HMDB Protein ID HMDBP12193
Secondary Accession Numbers None
Name 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Synonyms
  1. DXP reductoisomerase
  2. 1-deoxyxylulose-5-phosphate reductoisomerase
  3. 2-C-methyl-D-erythritol 4-phosphate synthase
Gene Name DXR
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
Pathways
  • Biosynthesis of secondary metabolites
  • Glycerophospholipid metabolism
  • isopentenyl diphosphate biosynthesis via DXP pathway
Reactions Not Available
GO Classification
Biological Process
isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
terpenoid biosynthetic process
Molecular Function
metal ion binding
1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NADPH binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 359
Molecular Weight 40326.11
Theoretical pI 9.023
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID B9KE50
UniProtKB/Swiss-Prot Entry Name DXR_CAMLR
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Miller WG, Wang G, Binnewies TT, Parker CT: The complete genome sequence and analysis of the human pathogen Campylobacter lari. Foodborne Pathog Dis. 2008 Aug;5(4):371-86. doi: 10.1089/fpd.2008.0101. [PubMed:18713059 ]