Identification |
HMDB Protein ID
| HMDBP12194 |
Secondary Accession Numbers
| None |
Name
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
Synonyms
|
- DXP reductoisomerase
- 1-deoxyxylulose-5-phosphate reductoisomerase
- 2-C-methyl-D-erythritol 4-phosphate synthase
|
Gene Name
| DXR |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). |
Pathways
|
- Biosynthesis of secondary metabolites
- isopentenyl diphosphate biosynthesis via DXP pathway
- Terpenoid backbone biosynthesis
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway |
terpenoid biosynthetic process |
Molecular Function |
metal ion binding |
1-deoxy-D-xylulose-5-phosphate reductoisomerase activity |
NADPH binding |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 376 |
Molecular Weight
| 42094.195 |
Theoretical pI
| 5.206 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| B9EBE2 |
UniProtKB/Swiss-Prot Entry Name
| DXR_MACCJ |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Baba T, Kuwahara-Arai K, Uchiyama I, Takeuchi F, Ito T, Hiramatsu K: Complete genome sequence of Macrococcus caseolyticus strain JCSCS5402, [corrected] reflecting the ancestral genome of the human-pathogenic staphylococci. J Bacteriol. 2009 Feb;191(4):1180-90. doi: 10.1128/JB.01058-08. Epub 2008 Dec 12. [PubMed:19074389 ]
|