Hmdb loader
Identification
HMDB Protein ID HMDBP12210
Secondary Accession Numbers None
Name 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Synonyms
  1. 4-diphosphocytidyl-2C-methyl-D-erythritol synthase
  2. MEP cytidylyltransferase
  3. MCT
Gene Name ISPD
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
Pathways
  • Biosynthesis of secondary metabolites
  • isopentenyl diphosphate biosynthesis via DXP pathway
  • Terpenoid backbone biosynthesis
Reactions Not Available
GO Classification
Biological Process
isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
terpenoid biosynthetic process
Molecular Function
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 236
Molecular Weight 25779.075
Theoretical pI 6.793
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID A1AEU1
UniProtKB/Swiss-Prot Entry Name ISPD_ECOK1
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Johnson TJ, Kariyawasam S, Wannemuehler Y, Mangiamele P, Johnson SJ, Doetkott C, Skyberg JA, Lynne AM, Johnson JR, Nolan LK: The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes. J Bacteriol. 2007 Apr;189(8):3228-36. doi: 10.1128/JB.01726-06. Epub 2007 Feb 9. [PubMed:17293413 ]