| Identification |
|---|
| HMDB Protein ID
| HMDBP12220 |
| Secondary Accession Numbers
| None |
| Name
| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) |
| Synonyms
|
- 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase
|
| Gene Name
| ISPG |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. |
| Pathways
|
- Biosynthesis of secondary metabolites
- isopentenyl diphosphate biosynthesis via DXP pathway
- Terpenoid backbone biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway |
| terpenoid biosynthetic process |
| Molecular Function |
| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity |
| 4 iron, 4 sulfur cluster binding |
| iron ion binding |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 380 |
| Molecular Weight
| 40808.785 |
| Theoretical pI
| 7.775 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q83N18 |
| UniProtKB/Swiss-Prot Entry Name
| ISPG_TROWT |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Raoult D, Ogata H, Audic S, Robert C, Suhre K, Drancourt M, Claverie JM: Tropheryma whipplei Twist: a human pathogenic Actinobacteria with a reduced genome. Genome Res. 2003 Aug;13(8):1800-9. doi: 10.1101/gr.1474603. [PubMed:12902375 ]
|
