Hmdb loader
Identification
HMDB Protein ID HMDBP12236
Secondary Accession Numbers None
Name 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Synonyms
  1. 4-diphosphocytidyl-2C-methyl-D-erythritol synthase
  2. MEP cytidylyltransferase
  3. MCT
Gene Name ISPD
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
Pathways
  • Biosynthesis of secondary metabolites
  • isopentenyl diphosphate biosynthesis via DXP pathway
  • Terpenoid backbone biosynthesis
Reactions Not Available
GO Classification
Biological Process
isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
terpenoid biosynthetic process
Molecular Function
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 237
Molecular Weight 27300.09
Theoretical pI 6.044
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q18CD1
UniProtKB/Swiss-Prot Entry Name ISPD_CLOD6
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Sebaihia M, Wren BW, Mullany P, Fairweather NF, Minton N, Stabler R, Thomson NR, Roberts AP, Cerdeno-Tarraga AM, Wang H, Holden MT, Wright A, Churcher C, Quail MA, Baker S, Bason N, Brooks K, Chillingworth T, Cronin A, Davis P, Dowd L, Fraser A, Feltwell T, Hance Z, Holroyd S, Jagels K, Moule S, Mungall K, Price C, Rabbinowitsch E, Sharp S, Simmonds M, Stevens K, Unwin L, Whithead S, Dupuy B, Dougan G, Barrell B, Parkhill J: The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet. 2006 Jul;38(7):779-86. Epub 2006 Jun 25. [PubMed:16804543 ]