Hmdb loader
Identification
HMDB Protein ID HMDBP12336
Secondary Accession Numbers None
Name Solute carrier family 25 member 36
Synonyms Not Available
Gene Name SLC25A36
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially cytosine and uracil (deoxy)nucleoside mono-, di-, and triphosphates by uniport and antiport mechanism. Also transports guanine but not adenine (deoxy)nucleotides. Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride, Mersalyl acid, p-hydroxymercuribenzoate). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration.
Pathways Not Available
Reactions Not Available
GO Classification
Biological Process
mitochondrial genome maintenance
regulation of mitochondrial membrane potential
pyrimidine nucleotide import into mitochondrion
pyrimidine nucleotide transport
mitochondrion organization
Cellular Component
mitochondrion
integral to membrane
mitochondrial inner membrane
Molecular Function
pyrimidine nucleotide transmembrane transporter activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 311
Molecular Weight 34282.29
Theoretical pI 8.572
Pfam Domain Function
Signals Not Available
Transmembrane Regions
  • 7-27;41-57;111-131;180-200;226-246;291-311;
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q96CQ1
UniProtKB/Swiss-Prot Entry Name S2536_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
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