Showing Protein Alpha-conotoxin ImII (HMDBP12434)
Identification | ||||||
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HMDB Protein ID | HMDBP12434 | |||||
Secondary Accession Numbers | None | |||||
Name | Alpha-conotoxin ImII | |||||
Synonyms |
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Gene Name | Not Available | |||||
Protein Type | Unknown | |||||
Biological Properties | ||||||
General Function | Not Available | |||||
Specific Function | Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks neuronal mammalian alpha-7 (human and rat) and alpha-3/beta-2 (human) and muscle alpha-1-beta-1-delta-epsilon (human) nAChRs (PubMed:12384509, PubMed:15609996). Acts voltage-independently (PubMed:12384509). Does not competes with alpha-bungarotoxin for binding to the receptor (PubMed:12384509, PubMed:15609996). Binds to a different site than alpha-conotoxin ImI (PubMed:15609996). | |||||
Pathways | Not Available | |||||
Reactions | Not Available | |||||
GO Classification |
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Cellular Location | Not Available | |||||
Gene Properties | ||||||
Chromosome Location | Not Available | |||||
Locus | Not Available | |||||
SNPs | Not Available | |||||
Gene Sequence | Not Available | |||||
Protein Properties | ||||||
Number of Residues | Not Available | |||||
Molecular Weight | 2096.46 | |||||
Theoretical pI | Not Available | |||||
Pfam Domain Function | Not Available | |||||
Signals | Not Available | |||||
Transmembrane Regions | Not Available | |||||
Protein Sequence | Not Available | |||||
External Links | ||||||
GenBank ID Protein | Not Available | |||||
UniProtKB/Swiss-Prot ID | Q8I6R5 | |||||
UniProtKB/Swiss-Prot Entry Name | CA12_CONIM | |||||
PDB IDs | Not Available | |||||
GenBank Gene ID | Not Available | |||||
GeneCard ID | Not Available | |||||
GenAtlas ID | Not Available | |||||
HGNC ID | Not Available | |||||
References | ||||||
General References |
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