| Identification |
|---|
| HMDB Protein ID
| HMDBP12591 |
| Secondary Accession Numbers
| None |
| Name
| Cobalamin biosynthesis protein CbiB |
| Synonyms
|
Not Available
|
| Gene Name
| CBIB |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. However, the true cosubstrate could be (R)-1-amino-2-propanol O-2-phosphate, leading to cobinamide phosphate. |
| Pathways
|
- adenosylcobalamin biosynthesis
- Biosynthesis of cofactors
- Porphyrin and chlorophyll metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| cobalamin biosynthetic process |
| Cellular Component |
| plasma membrane |
| integral to membrane |
| Molecular Function |
| ABC-type vitamin B12 transporter activity |
| threonine-phosphate decarboxylase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 319 |
| Molecular Weight
| 35500.05 |
| Theoretical pI
| 9.243 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
- 56-76;82-102;153-173;296-316;
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q5PDS9 |
| UniProtKB/Swiss-Prot Entry Name
| CBIB_SALPA |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - McClelland M, Sanderson KE, Clifton SW, Latreille P, Porwollik S, Sabo A, Meyer R, Bieri T, Ozersky P, McLellan M, Harkins CR, Wang C, Nguyen C, Berghoff A, Elliott G, Kohlberg S, Strong C, Du F, Carter J, Kremizki C, Layman D, Leonard S, Sun H, Fulton L, Nash W, Miner T, Minx P, Delehaunty K, Fronick C, Magrini V, Nhan M, Warren W, Florea L, Spieth J, Wilson RK: Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet. 2004 Dec;36(12):1268-74. doi: 10.1038/ng1470. Epub 2004 Nov 7. [PubMed:15531882 ]
|
