| Identification |
|---|
| HMDB Protein ID
| HMDBP12595 |
| Secondary Accession Numbers
| None |
| Name
| Renin |
| Synonyms
|
- Angiotensinogenase
|
| Gene Name
| REN |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
| Pathways
|
- Diabetic cardiomyopathy
- Renin secretion
- Renin-angiotensin system
|
| Reactions
| Not Available |
| GO Classification
|
| Cellular Component |
| extracellular region |
| membrane |
| Molecular Function |
| aspartic-type endopeptidase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 400 |
| Molecular Weight
| 44037.875 |
| Theoretical pI
| 6.321 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q9TSZ1 |
| UniProtKB/Swiss-Prot Entry Name
| RENI_CALJA |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Valdenaire O, Breu V, Giller T, Bur D, Fischli W: Cloning and characterization of marmoset renin: comparison with human renin. J Cardiovasc Pharmacol. 1999 Dec;34(6):893-7. doi: 10.1097/00005344-199912000-00018. [PubMed:10598135 ]
|
