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Showing Protein Glucan 1,3-beta-glucosidase 2 (HMDBP12650)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 metabolites
Identification
HMDB Protein ID HMDBP12650
Secondary Accession Numbers None
Name Glucan 1,3-beta-glucosidase 2
Synonyms
  1. Exo-1,3-beta-glucanase 2
Gene Name EXG2
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. EXG2 is not heavily involved in the exoglucanase function of the adhesion process.
Pathways
  • Starch and sucrose metabolism
Reactions Not Available
GO Classification
Biological Process
cell wall organization
cellular glucan metabolic process
glucan catabolic process
Cellular Component
cell surface
extracellular region
anchored to plasma membrane
Molecular Function
beta-glucosidase activity
glucan exo-1,3-beta-glucosidase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 479
Molecular Weight 54534.11
Theoretical pI 5.53
Pfam Domain Function
Signals
  • 1-21;
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q5AIA1
UniProtKB/Swiss-Prot Entry Name EXG2_CANAL
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Jones T, Federspiel NA, Chibana H, Dungan J, Kalman S, Magee BB, Newport G, Thorstenson YR, Agabian N, Magee PT, Davis RW, Scherer S: The diploid genome sequence of Candida albicans. Proc Natl Acad Sci U S A. 2004 May 11;101(19):7329-34. doi: 10.1073/pnas.0401648101. Epub 2004 May 3. [PubMed:15123810 ]
  2. van het Hoog M, Rast TJ, Martchenko M, Grindle S, Dignard D, Hogues H, Cuomo C, Berriman M, Scherer S, Magee BB, Whiteway M, Chibana H, Nantel A, Magee PT: Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. Genome Biol. 2007;8(4):R52. doi: 10.1186/gb-2007-8-4-r52. [PubMed:17419877 ]
  3. Muzzey D, Schwartz K, Weissman JS, Sherlock G: Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Genome Biol. 2013;14(9):R97. doi: 10.1186/gb-2013-14-9-r97. [PubMed:24025428 ]
  4. De Groot PW, Hellingwerf KJ, Klis FM: Genome-wide identification of fungal GPI proteins. Yeast. 2003 Jul 15;20(9):781-96. doi: 10.1002/yea.1007. [PubMed:12845604 ]
  5. Newport G, Kuo A, Flattery A, Gill C, Blake JJ, Kurtz MB, Abruzzo GK, Agabian N: Inactivation of Kex2p diminishes the virulence of Candida albicans. J Biol Chem. 2003 Jan 17;278(3):1713-20. doi: 10.1074/jbc.M209713200. Epub 2002 Nov 4. [PubMed:12419804 ]
  6. Castillo L, Martinez AI, Garcera A, Garcia-Martinez J, Ruiz-Herrera J, Valentin E, Sentandreu R: Genomic response programs of Candida albicans following protoplasting and regeneration. Fungal Genet Biol. 2006 Feb;43(2):124-34. doi: 10.1016/j.fgb.2005.12.002. Epub 2006 Feb 7. [PubMed:16455273 ]
  7. Cabezon V, Llama-Palacios A, Nombela C, Monteoliva L, Gil C: Analysis of Candida albicans plasma membrane proteome. Proteomics. 2009 Oct;9(20):4770-86. doi: 10.1002/pmic.200800988. [PubMed:19824013 ]
  8. Singh RP, Prasad HK, Sinha I, Agarwal N, Natarajan K: Cap2-HAP complex is a critical transcriptional regulator that has dual but contrasting roles in regulation of iron homeostasis in Candida albicans. J Biol Chem. 2011 Jul 15;286(28):25154-70. doi: 10.1074/jbc.M111.233569. Epub 2011 May 18. [PubMed:21592964 ]
  9. Tsai PW, Yang CY, Chang HT, Lan CY: Characterizing the role of cell-wall beta-1,3-exoglucanase Xog1p in Candida albicans adhesion by the human antimicrobial peptide LL-37. PLoS One. 2011;6(6):e21394. doi: 10.1371/journal.pone.0021394. Epub 2011 Jun 21. [PubMed:21713010 ]
  10. Rohm M, Lindemann E, Hiller E, Ermert D, Lemuth K, Trkulja D, Sogukpinar O, Brunner H, Rupp S, Urban CF, Sohn K: A family of secreted pathogenesis-related proteins in Candida albicans. Mol Microbiol. 2013 Jan;87(1):132-51. doi: 10.1111/mmi.12087. Epub 2012 Dec 10. [PubMed:23136884 ]