Hmdb loader
Identification
HMDB Protein ID HMDBP12789
Secondary Accession Numbers None
Name Protein BANP
Synonyms
  1. BEN domain-containing protein 1
  2. Btg3-associated nuclear protein
  3. Scaffold/matrix-associated region-1-binding protein
Gene Name BANP
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification
Biological Process
multicellular organismal development
cell cycle
chromatin organization
positive regulation of transcription, DNA-dependent
negative regulation of protein catabolic process
regulation of signal transduction by p53 class mediator
protein localization to nucleus
Cellular Component
nucleoplasm
nuclear body
Molecular Function
identical protein binding
DNA binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 519
Molecular Weight 56494.08
Theoretical pI 5.488
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q8N9N5
UniProtKB/Swiss-Prot Entry Name BANP_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
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