Identification |
HMDB Protein ID
| HMDBP12844 |
Secondary Accession Numbers
| None |
Name
| 4-hydroxythreonine-4-phosphate dehydrogenase |
Synonyms
|
- 4-(phosphohydroxy)-L-threonine dehydrogenase
|
Gene Name
| PDXA |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). |
Pathways
|
- Biosynthesis of cofactors
- pyridoxine 5'-phosphate biosynthesis
- Vitamin B6 metabolism
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
pyridoxine biosynthetic process |
pyridoxal phosphate biosynthetic process |
Cellular Component |
cytoplasm |
Molecular Function |
cobalt ion binding |
NAD binding |
magnesium ion binding |
zinc ion binding |
4-hydroxythreonine-4-phosphate dehydrogenase activity |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 307 |
Molecular Weight
| 33705.61 |
Theoretical pI
| 7.205 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q9ZJ28 |
UniProtKB/Swiss-Prot Entry Name
| PDXA_HELPJ |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Alm RA, Ling LS, Moir DT, King BL, Brown ED, Doig PC, Smith DR, Noonan B, Guild BC, deJonge BL, Carmel G, Tummino PJ, Caruso A, Uria-Nickelsen M, Mills DM, Ives C, Gibson R, Merberg D, Mills SD, Jiang Q, Taylor DE, Vovis GF, Trust TJ: Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori. Nature. 1999 Jan 14;397(6715):176-80. doi: 10.1038/16495. [PubMed:9923682 ]
|