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Identification
HMDB Protein ID HMDBP12846
Secondary Accession Numbers None
Name Phosphoserine aminotransferase
Synonyms
  1. PSAT
  2. Endometrial progesterone-induced protein
  3. Phosphohydroxythreonine aminotransferase
  4. EPIP
Gene Name PSAT1
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
Pathways
  • Biosynthesis of amino acids
  • Biosynthesis of cofactors
  • Carbon metabolism
  • Cysteine and methionine metabolism
  • Glycine, serine and threonine metabolism
  • L-serine biosynthesis
  • pyridoxine 5'-phosphate biosynthesis
  • Vitamin B6 metabolism
Reactions Not Available
GO Classification
Biological Process
L-serine biosynthetic process
Molecular Function
O-phospho-L-serine:2-oxoglutarate aminotransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 370
Molecular Weight 40620.715
Theoretical pI 7.929
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P10658
UniProtKB/Swiss-Prot Entry Name SERC_RABIT
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. van der Zel A, Lam HM, Winkler ME: Extensive homology between the Escherichia coli K-12 SerC(PdxF) aminotransferase and a protein encoded by a progesterone-induced mRNA in rabbit and human endometria. Nucleic Acids Res. 1989 Oct 25;17(20):8379. doi: 10.1093/nar/17.20.8379. [PubMed:2682527 ]
  2. Misrahi M, Atger M, Milgrom E: A novel progesterone-induced messenger RNA in rabbit and human endometria. Cloning and sequence analysis of the complementary DNA. Biochemistry. 1987 Jun 30;26(13):3975-82. doi: 10.1021/bi00387a035. [PubMed:3651428 ]