| Identification |
|---|
| HMDB Protein ID
| HMDBP12926 |
| Secondary Accession Numbers
| None |
| Name
| Chorismate synthase |
| Synonyms
|
- CS
- 5-enolpyruvylshikimate-3-phosphate phospholyase
|
| Gene Name
| AROC |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. |
| Pathways
|
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- chorismate biosynthesis
- Phenylalanine, tyrosine and tryptophan biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| cellular amino acid biosynthetic process |
| aromatic amino acid family biosynthetic process |
| chorismate biosynthetic process |
| Molecular Function |
| chorismate synthase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 377 |
| Molecular Weight
| 39780.67 |
| Theoretical pI
| 7.892 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| B4RHV8 |
| UniProtKB/Swiss-Prot Entry Name
| AROC_PHEZH |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Luo Y, Xu X, Ding Z, Liu Z, Zhang B, Yan Z, Sun J, Hu S, Hu X: Complete genome of Phenylobacterium zucineum--a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562. BMC Genomics. 2008 Aug 13;9:386. doi: 10.1186/1471-2164-9-386. [PubMed:18700039 ]
|
