Identification |
HMDB Protein ID
| HMDBP12938 |
Secondary Accession Numbers
| None |
Name
| Chorismate synthase |
Synonyms
|
- CS
- 5-enolpyruvylshikimate-3-phosphate phospholyase
|
Gene Name
| AROC |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. |
Pathways
|
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- chorismate biosynthesis
- Phenylalanine, tyrosine and tryptophan biosynthesis
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
cellular amino acid biosynthetic process |
aromatic amino acid family biosynthetic process |
chorismate biosynthetic process |
Molecular Function |
chorismate synthase activity |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 388 |
Molecular Weight
| 42534.555 |
Theoretical pI
| 8.227 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| C0M8T9 |
UniProtKB/Swiss-Prot Entry Name
| AROC_STRE4 |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Holden MT, Heather Z, Paillot R, Steward KF, Webb K, Ainslie F, Jourdan T, Bason NC, Holroyd NE, Mungall K, Quail MA, Sanders M, Simmonds M, Willey D, Brooks K, Aanensen DM, Spratt BG, Jolley KA, Maiden MC, Kehoe M, Chanter N, Bentley SD, Robinson C, Maskell DJ, Parkhill J, Waller AS: Genomic evidence for the evolution of Streptococcus equi: host restriction, increased virulence, and genetic exchange with human pathogens. PLoS Pathog. 2009 Mar;5(3):e1000346. doi: 10.1371/journal.ppat.1000346. Epub 2009 Mar 27. [PubMed:19325880 ]
|