Identification |
HMDB Protein ID
| HMDBP12942 |
Secondary Accession Numbers
| None |
Name
| Chorismate synthase |
Synonyms
|
- CS
- 5-enolpyruvylshikimate-3-phosphate phospholyase
|
Gene Name
| AROC |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. |
Pathways
|
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- chorismate biosynthesis
- Phenylalanine, tyrosine and tryptophan biosynthesis
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
cellular amino acid biosynthetic process |
aromatic amino acid family biosynthetic process |
chorismate biosynthetic process |
Molecular Function |
chorismate synthase activity |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 388 |
Molecular Weight
| 42539.625 |
Theoretical pI
| 7.459 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q1JHJ1 |
UniProtKB/Swiss-Prot Entry Name
| AROC_STRPD |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Beres SB, Richter EW, Nagiec MJ, Sumby P, Porcella SF, DeLeo FR, Musser JM: Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus. Proc Natl Acad Sci U S A. 2006 May 2;103(18):7059-64. doi: 10.1073/pnas.0510279103. Epub 2006 Apr 24. [PubMed:16636287 ]
|