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Identification
HMDB Protein ID HMDBP13002
Secondary Accession Numbers None
Name Pyridoxine 5'-phosphate synthase
Synonyms
  1. PNP synthase
Gene Name PDXJ
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
Pathways
  • Biosynthesis of cofactors
  • pyridoxine 5'-phosphate biosynthesis
  • Vitamin B6 metabolism
Reactions Not Available
GO Classification
Biological Process
pyridoxine biosynthetic process
Cellular Component
cytoplasm
Molecular Function
pyridoxine 5'-phosphate synthase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 233
Molecular Weight 25962.77
Theoretical pI 6.129
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q2GJT4
UniProtKB/Swiss-Prot Entry Name PDXJ_ANAPZ
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Dunning Hotopp JC, Lin M, Madupu R, Crabtree J, Angiuoli SV, Eisen JA, Seshadri R, Ren Q, Wu M, Utterback TR, Smith S, Lewis M, Khouri H, Zhang C, Niu H, Lin Q, Ohashi N, Zhi N, Nelson W, Brinkac LM, Dodson RJ, Rosovitz MJ, Sundaram J, Daugherty SC, Davidsen T, Durkin AS, Gwinn M, Haft DH, Selengut JD, Sullivan SA, Zafar N, Zhou L, Benahmed F, Forberger H, Halpin R, Mulligan S, Robinson J, White O, Rikihisa Y, Tettelin H: Comparative genomics of emerging human ehrlichiosis agents. PLoS Genet. 2006 Feb;2(2):e21. doi: 10.1371/journal.pgen.0020021. Epub 2006 Feb 17. [PubMed:16482227 ]